Suomeksi
 
 
Bio-inspired biomaterials for bone regeneration

Description of the research

Main goal of our research is to find a solution for bone diseases in elderly population, such as osteoarthritis and osteoporosis. Our research is aiming at multidisciplinary collaborations between medicine, cell biology and materials science.
My current research interest includes:
 
• Bio-inspired biomaterials to enhance bone regeneration through the manipulation of bone cells (osteoblasts, osteocytes and osteoclasts)
• New parameters for the evaluation of bone quality using knowledge of materials science
• Mechanism of osteolysis in aseptic loosening 

Group members

We are looking for students (undergraduates, masters, Ph.D. candidates all welcome)!

Please feel free to contact/ visit us.

Selected publications

Total number: 60 peer-reviewed papers, 18 proceedings, 4 reviews
 
Selected 5 publications during 2012-2017
1. Nakamura M, Hori N, Ando H, Namba S, Toyama T, Nishimiya N, Yamashita K. Surface Free Energy Predominates in Cell Adhesion to Hydroxyapatite through Wettability. Mater Sci Eng C 2016: 62, 283-292. IF=5.080, 6/33 Journals in Materials Science, Biomaterials.

2. Nakamura M, Hiratai R, Hentunen T, Salonen J, Yamashita K. Hydroxyapatite with High Carbonate Substitutions Promotes Osteoclast Resorption through Osteocyte-like Cells. ACS Biomater Sci Eng 2016: 2 (2), 259-267. IF=4.432, 9/33 Journals in Materials Science, Biomaterials. 

3. Nakamura M, Hentunen T, Salonen J, Nagai A, Yamashita K. Characterization of bone mineral-resembling biomaterials for optimizing human osteoclast differentiation and resorption. J Biomed Mater Res A, 2013: 101A (11), 3141-3151. IF=3.231, 16/33 Journals in Materials Science, Biomaterials. 

4. Nakamura M, Hiratai R, Yamashita K. Bone mineral as an electrical energy reservoir. J Biomed Mater Res A 2012: 100A, 1368-1374. IF=3.231, 16/33 Journals in Materials Science, Biomaterials.

5. Nakamura M, Soya T, Hiratai R, Nagai A, Hashimoto K, Morita I, Yamashita K. Endothelial cell migration and morphogenesis on silk fibroin scaffolds including hydroxyapatite electret. J Biomed Mater Res A 2012: 100A, 969-977. IF=3.231, 16/33 Journals in Materials Science, Biomaterials.

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