Suomeksi
 
 
Positron emission tomography (PET) in the diagnostics of infections and autoimmune vasculitis

​​Description of research

Positron emission tomography (PET) in the diagnostics of infections and autoimmune vasculitis
Positron emission tomography (PET) in the diagnostics of infections and autoimmune vasculitis: a) infective endocarditis, device infections b) bacteremic Staphylococcus aureus infection c) vasculitis.

Neuroborreliosis study
Neuroborreliosis study: a) The epidemiology, clinical findings and development of laboratory diagnostic tests, b)randomized comparison of oral to intravenous antibiotic treatment (together with HUCH).

Leukocyte surface receptor study: A novel multiparametric flow-cytometric bacterial infection marker (BIindex)
Leukocyte surface receptor study: a) expression patterns in infectious/inflammatory diseases, b) flow cytometric analysis for distinguishing between bacterial and viral infections.

Studies on patients with invasive group A and group G streptococcal (iGAS and iGGS) infection
Prospective studies on patients with invasive group A and group G streptococcal infection: a) epidemiology, predisposing factors and outcome of infection b) pathogenesis of iGAS and iGGS infections applying e.g. transcriptome analysis of patients (together with Tampere University Hospital)

Infective endocarditis in Finland
Infective endocarditis in Finland: epidemiology, etiological agents, predisposing factors, treatment and outcome of infection.

Members of the research group

Senior researchers:
Laura Airas MD, PhD;
Ulla Hohenthal, MD, PhD, docent
Jukka Hytönen, MD, PhD, docent
Päivi Jalava-Karvinen, MD, PhD
Juhani Knuuti MD, PhD, professor
Ville Kytö, MD, PhD, docent
Jari Nuutila, PhD, docent
Jaana Vuopio MD, PhD, professor

Doctoral candidates:
Elina Ahtela MD
Elisa Kortela MD
Soile Salomäki MD
Johanna Vilhonen MD

Selected publications

Hytönen J, Kortela E, Waris M, Puustinen J, Salo J, Oksi J. CXCL13 and neopterin concentrations in cerebrospinal fluid of patients with Lyme neuroborreliosis and other diseases that cause neuroinflammation. Journal of Neuroinflammation 2014 Jun 11;11:103. doi: 10.1186/1742-2094-11-103.

Oksi J. Clostridium difficile infection: review with special interest in hematologic patients. Drugs and Cell Therapies in Hematology 2014; 3 (No 2):89-100. doi: http://dx.doi.org/10.4081/dcth.2014.63

Salomäki SP, Saraste A, Kemppainen J, Bax JJ, Knuuti J, Nuutila P, Seppänen M, Roivainen A, Airaksinen J, Pirilä L, Oksi J, Hohenthal U. 18F-FDG Positron Emission Tomography / Computed tomography in Infective Endocarditis. J Nucl Cardiol. 2015 Dec 9. [Epub ahead of print]. DOI: 10.1007/s12350-015-0325-y PMID: 26662063

Metsi J, Vuorela M, Kantele A, Kuusi M, Oksi J. Puutiaisaivokuume Suomessa 2010-2012. Duodecim 2015;131(15):1367-75.

Hytönen J, Khawaja T, Grönroos JO, Jalava A, Meri S, Oksi J. Toisintokuume. Duodecim 2016;132:1952-6.

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 Professor Jarmo Oksi