Suomeksi
 
 
Minimally invasive surgery/Acute appendicitis

Desription of the research

From the very beginning of my scientific career and later througout it, I have focused on general surgery, particularly on GI surgery: from basic to translational and clinical science. I have been interested in the pathogenesis, pathophysiology, diagnosis, severity assessment and treatment of various surgical infections and inflammatory states.

My major study topics include also pancreatobiliary diseases and colorectal cancer. During the last decade, I have focused my main scientific interest on prospective ramdomized multicenter controlled trials (10 at present ongoing) on endoscopic, laparoscopic ja emergency surgery, particularly on endoscopic and laparoscopic biliary and pancreatic surgery and on the treatment of acute appendicitis.

​Members of the research group

Minimally invasive surgery group (ANDRE - Allied Nordic Network for the Develompment and Research in Endoscopy)
Juha Grönroos
Leena Kylänpää
Arto Saarela
Urban Arnelo
Fredrik Swahn
Ervin Toth
Björn Lindqvist
Lars Aabakken
Truls Hauge
Per Ejstrud
Gunnar Qvigstad
 
Acute appendicitis group
Juha Grönroos
Paulina Salminen
Johanna Virtanen
Saija Hurme
Ari Leppäniemi
Ville Sallinen
Johanna Laukkarinen
Pia Nordqvist
Tuomo Rantanen
Hannu Paajanen
Tero Rautio
Sanna Meriläinen
 
Doctoral candidates
Elina Lietzen
Suvi Sippola
Jussi Haijanen
Anu Carpelan
Leena-Mari Mäntymäki
Tero Irmola
Tuomas Lehtoranta

Selected publications

Kauhanen S, Rinta-Kiikka I, Kemppainen J, Grönroos J, Kajander S, Seppänen M, Alanen K, Gullichsen R, Nuutila P, Ovaska J. Accuracy of 18F-FDG PET/CT, multidertector CT, and MR imaging in the diagnosis of pancreatic cysts: a prospective single-center study. J Nucl Med 2015;56:1163-1168.
 
Räty S, Pulkkinen J, Nordback I, Sand J, Victorzon M, Grönroos J, Helminen H, Kuusanmäki P, Nordström P, Paajanen H. Can laparoscopic cholecystectomy prevent recurrent idiopathic acute pancreatitis? A prospective randomized multicenter trial. Ann Surg 2015;262:736-741.
 
Salminen P, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Tuominen R, Hurme S, Virtanen J, Mecklin J-P, Sand J, Jartti A, Rinta-Kiikka I, Grönroos JM. Antibiotic therapy vs. appendectomy for the treatment of uncomplicated acute appendicitis.The APPAC randomized clinical trial. JAMA 2015;313:2340-
2348.
 
Salminen P, Grönroos JM. Treatment of uncomplicated acute appendicitis. JAMA 2015;314:1403-1404.
 
Sippola S, Grönroos J, Tuominen R, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Hurme S, Salminen P. Economic evaluation of antibiotic therapy versus appendectomy for the treatment of uncomplicated acute appendicitis: results of the APPAC randomized clinical trial. Br J Surg, in press 2017.
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 Prof. Juha Grönroos

 
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