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Longitudinal Phenotypic and Genotypic Profiling of Asthma and COPD patients

​Description of Research

  1. Longitudinal Phenotypic and Genotypic Profiling of Asthma and COPD patients and Development of Analytical Methods for Clinical Outcomes
  2. Systematic use of Electronic Retrospective Health Care Data in development of new diagnostics and in the evaluation of efficacy/adverse events related to given treatments
Systematic use of Electronic Retrospective Health Care Data in development of new diagnostics and in the evaluation of efficacy/adverse events related to given treatments

Members of the research group

Jukka Koskela, MD PhD post-doc
Milla Katajisto, MD doctoral candidate
Eveliina Hirvonen, Medical Student
Mikhail Stepanov, Data Scientist
Anna Hammais, Bioinformatics
Mikko Koskinen, PhD Data Scientist
Arho Virkki, PhD Project manager

Selected publications

Gao J, Iwamoto H, Koskela J, Alenius H, Hattori N, Kohno N, Laitinen T, Mazur W & Pulkkinen V: Characterization of sputum biomarkers for asthma-COPD overlap syndrome. J Chr Obstruct Pulmon Dis (in press 2016)(IP 3.1)
 
Myllylä M, Anttalainen U, Saaresranta T & Laitinen T: Individual changes in BMI and CPAP usage development during long-term CPAP therapy – A 5-year-follow-up study. Journal of Clinical Sleep Medicine 2016;12:519-28.(IP 2.8)
 
Kupiainen H, Kuokkanen M, Lindqvist A, Jonsdottir, Kilpeläinen M, Virtamo H & Laitinen T: CHRNA5/CHRNA3 locus associates with increased mortality among smokers. J Chr Obstruct Pulmon Dis 2016; 11: 1-7.(IP 3.1)
 
Koskela J, Kupiainen H, Katajisto M, Kilpeläinen M, Lindqvist A & Laitinen T: FEV1 measures show trends and identify constant decliners among COPD patients. J Chron Obstruct Pulmon Dis 2016; 25: 1-6. (IP 3.1)
 
Katajisto M, Koskela J, Lindqvist A, Kilpeläinen M & Laitinen T: Physical activity among COPD patients associates to the decreased use of short acting bronchodilators and the number of exacerbations. Journal of Respiratory Medicine 2015; 109: 1320-5.(IP 3.0)

 

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