Respiratory tract infections in children: epidemiology, management, prevention, and total impact on the society

​​​Description of research

This clinical research project focuses on timely and clinically important questions in the field of respiratory infections and their complications in children. The goal of the project is to produce reliable and useful information that would be directly applicable to everyday clinical practice and that could also guide health carerelated political decision-making.

Members of the research group

Senior researchers
Santtu Heinonen, MD, PhD
Heli Silvennoinen, MD, PhD
Janne Kataja, MD, PhD
Tuomo Puhakka, MD, PhD

Doctoral candidates
Heikki Valkonen
Maria Maunula
Erika Uusitupa

Selected publications

Heikkinen T, Ikonen N, Ziegler T. Impact of influenza B lineage-level mismatch between trivalent seasonal influenza vaccines and circulating viruses, 1999-2012. Clin Infect Dis 2014;59:1519-24.

Mazur NI, Martinón-Torres F, Baraldi E, et al. Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics. Lancet Respir Med 2015;3:888-900.

Silvennoinen H, Huusko T, Vuorinen T, Heikkinen T. Comparative burden of influenza A/H1N1, A/H3N2 and B infections in children treated as outpatients. Pediatr Infect Dis J 2015;34:1081-5.

Nagy L, Heikkinen T, Sackeyfio A, Pitman R. The clinical impact and cost effectiveness of quadrivalent versus trivalent influenza vaccination in Finland. PharmacoEconomics 2016;34:939-51.

Heikkinen T, Ojala E, Waris M. Clinical and socioeconomic burden of respiratory syncytial virus infection in children. J Infect Dis 2017;215:17-23.


 Prof. Terho Heikkinen