Suomeksi
 
 
Molecular epidemiology, carriage and antimicrobial susceptibility of bacterial pathogens

Description of Research

Study topics are:

  • Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci, ge-nomic evolution of the bacterium, host susceptibility and risk factors to these infections.
  • Molecular epidemiology, prevention and surveillance of multiresistant bacterial infections.

Current research areas:

  • Molecular markers for disease and carriage of Group A streptococci
  • Molecular evolution of S.pyogenes
  • Life stock associated MRSA
  • Molecular epidemiology of MRSA in Finland
  • Carriage of ESBL in healthy population  (Northern Dimension Antibiotic Resistance Study, NoDARS)

List of Personnel

Kirsi Gröndahl-Yli-Hannuksela, M.Sc.
Laura Lindholm, M.Sc., Ph.D. fellow
Kati Räisänen, M.Sc.,Ph.D. fellow
Kai Puhakainen, B.Sc.
Miia Laine, M.D., Ph.D.
Marianne Gunell, Ph.D.
Olli Likitalo, M.D.
Mikko Talja, med.student
Francesca Latronico, D.V.M., Ph.D.
Mari Virta, laboratory technician

Selected Publications

Hannula-Jouppi K, Massinen S, Siljander T, Mäkelä S, Kivinen K, Leinonen R, Jiao H, Aitos P, Karppelin M, Vuopio J, Syrjänen J, Kere J. Genetic susceptibility to non-necrotizing ery-sipelas/cellulitis. PLoS One. 2013;8(2):e56225.

Nasser W, Beres SB, Olsen RJ, Dean MA, Rice KA, Long SW, Kristinsson KG, Gottfredsson M, Vuopio J, Raisanen K, Caugant DA, Steinbakk M, Low DE, McGeer A, Darenberg J, Hen-riques-Normark B, Van Beneden CA, Hoffmann S, Musser JM. Evolutionary pathway to in-creased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences. Proc Natl Acad Sci U S A. 2014 Apr 14.

Jokinen E, Laine J, Huttunen R, Arvola P, Vuopio J, Lindholm L, Vuento R,
Syrjänen J. Combined interventions are effective in MRSA control. Infect Dis
(Lond). 2015 Nov;47(11):805-11.

Zhu L, Olsen RJ, Nasser W, Beres SB, Vuopio J, Kristinsson KG, Gottfredsson M,
Porter AR, DeLeo FR, Musser JM. A molecular trigger for intercontinental
epidemics of group A Streptococcus. J Clin Invest. 2015 Aug 10. pii: 82478. doi:
10.1172/JCI82478.

Smit PW, Lindholm L, Lyytikäinen O, Jalava J, Pätäri-Sampo A, Vuopio J.
Epidemiology and emm types of invasive group A streptococcal infections in
Finland, 2008-2013. Eur J Clin Microbiol Infect Dis. 2015 Aug 21. [Epub ahead of
print]

Keywords:
Tags: