Suomeksi
 
 
Bioorganic Group
People
 
Professor Pasi Virta
 
Dr. Satu Mikkola, Dr. Mikko Ora, Dr. Tuomas Lönnberg, Dr. Heidi Korhonen, Dr Petri Tähtinen, Dr Sajal Maity, Dr Jianwei Li

Ms. Marika Karskela, M Sc; Mr. Vyacheslav Kungurtsev, M Sc; Satish Jadhav, M Sc; Lotta Granqvist, M Sc; Mr Ville Tähtinen, M Sc; Mr Petja Rosenqvist, MSc.

 

 

 

 

 
 
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 Recent Dissertations

 
Golubev, Oleg: Recognition of nuckeic acids by metal ion complexes. 2016
Lain, Luigi: The role of amine phosphate interactions in the cleavage and isomerization of RNA phosphodiester linkages. 2016
Taherpour, Sharmin: Metal-ion-binding oligonucleotides: high-affinity probes for nucleic acid sequences.
2015
Leisvuori, Anna: Prodrug strategies of antiviral nucleotides: studies on enzymatically and thermally removable phosphate protecting groups. 2015
Gimenez Molina, Alejandro: Synthesis of short oligonucleotides on a soluble support by the phosphoramidite method. 2015
Kiuru, Emilia: Nucleotides as antiviral compounds: on the feasibility of an esterase-dependent prodrug strategy for 2-5A. 2015
 

 Recent publications

 

Ukale, D.; Shinde, V.S.; Lönnberg, T., 5-Mercuricytosine: An organometallic Janus Nucleobase. Chem. Eur. J.  2016, 22, 7917-23

Granqvist, L.; Virta, P., 2´-O-[(4-CF3-triazol-1-yl)methyl]uridine – A sensitive F-19 NMR sensor for the detection of RNA secondary structures. J. Org. Chem. 2015, 80, 7961-7970.

Lönnberg, T.; Hutchinson, M.; Rokita, S., Selective alkylation of C-rich bulge motifs in nucleic acids by quinone methide derivative. Chem. Eur. J. 2015, 21, 13127-13136  

Sontakke, V.; Lönnberg, H.; Ora, M., 4-Aetylthio-2,2-dimethyl-3-oxobutyl and 4-(tert-butyl-disulfanyl)-2,2-dimethyl-3-oxobutyl group as protecting groups of nucleoside 5´-phosphoramidates derived from L-alanine methyl ester, Eur. J. Org. Chem. 2015, 5004-5012

Dano, M.; Elmeranta, M.; Hodgson, D. R. W., Jaakkola, J.; Korhonen, H.; Mikkola, S., Metal ion-promoted cleavage of nucleoside diphosphosugars: a model for reactions of phosphodiester bonds in carbohydrates. J. Biol. Inorg. Chem.2015, 20, 1299-1306.