Harry Scheinin profile picture
Harry
Scheinin
Docent, Institute of Biomedicine
Turku PET Centre
MD

Areas of expertise

Anesthesiology
Clinical Pharmacology
Neuroscience
Positron Emission Tomography

Biography

Harry Scheinin leads the Anesthesia Mechanisms Research Group at the University of Turku, Finland, and has studied the human neurobiology of anesthetic agents for 20 years. He has collaborated with Professor Antti Revonsuo since 2005.

Research

We try to explore the neural correlates of human consciousness using, e.g., modern imaging methods. We aim to separate consciousness from responsiveness, connectedness from disconnection and to compare unconsciousness of physiological sleep with that induced by anesthetic agents. Finding new tools for the distinction of consciousness, connectedness and responsiveness would be groundbreaking and could represent a major leap forward in understanding human consciousness. The results could also help in developing new EEG-based methods to objectively measure consciousness and the depth of general anesthesia. 

Publications

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Spoken words are processed during dexmedetomidine-induced unresponsiveness (2018)

British Journal of Anaesthesia
Kallionpää R.E., Scheinin A., Kallionpää R.A., Sandman N., Kallioinen M., Laitio R., Laitio T., Kaskinoro K., Kuusela T., Revonsuo A., Scheinin H., Valli K.
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Comparative effects of dexmedetomidine, propofol, sevoflurane, and S-ketamine on regional cerebral glucose metabolism in humans: a positron emission tomography study (2018)

British Journal of Anaesthesia
Laaksonen L., Kallioinen M., Långsjö J., Laitio T., Scheinin A., Scheinin J., Kaisti K., Maksimow A., Kallionpää R.E., Rajala V., Johansson J., Kantonen O., Nyman M., Sirén S., Valli K., Revonsuo A., Solin O., Vahlberg T., Alkire M., Scheinin H.
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Inhaled Xenon Attenuates Myocardial Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest The Xe-Hypotheca Trial (2017)

Journal of the American College of Cardiology
Olli Arola, Antti Saraste, Ruut Laitio, Juhani Airaksinen, Marja Hynninen, Minna Bäcklund, Emmi Ylikoski, Johanna Wennervirta, Mikko Pietilä, Risto O. Roine, Veli-Pekka Harjola, Jussi Niiranen, Kirsi Korpi, Marjut Varpula, Harry Scheinin, Mervyn Maze, Tero Vahlberg, Timo Laitio
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest A Randomized Clinical Trial (2016)

JAMA: Journal of the American Medical Association
Laitio R, Hynninen M, Arola O, Virtanen S, Parkkola R, Saunavaara J, Roine RO, Grönlund J, Ylikoski E, Wennervirta J, Bäcklund M, Silvasti P, Nukarinen E, Tiainen M, Saraste A, Pietilä M, Airaksinen J, Valanne L, Martola J, Silvennoinen H, Scheinin H, Harjola VP, Niiranen J, Korpi K, Varpula M, Inkinen O, Olkkola KT, Maze M, Vahlberg T, Laitio T
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))