Laura Ekblad profile picture
Laura
Ekblad
Docent, Department of Clinical Medicine
MD, PhD
Specialist in Geriatrics and Family Medicine. Senior researcher, Turku Alzheimer Imaging Group, Turku PET Centre.

Contact

Links

Turku Alzheimer Imaging Group
ResearchGate
ORCID

Areas of expertise

positron emission tomography
Alzheimer´s Disease
Insulin resistance
cognition
memory disorders

Research

My research focuses on early risk factors for memory disorders, especially Alzheimer´s disease. I am particularly interested in the associations between metabolic risk factors (insulin resistance, glucose intolerance, obesity) and cognitive decline.

Our lab uses multimodal neuroimaging (PET-imaging, MRI) combined with blood and CSF biomarkers and cognitive testing to explore the association between different risk factors and early cerebral changes of memory disorders.

I also run a project that examines possible cardiac side effects of anti-dementia agents in elderly memory clinic patients. 

Publications

Sort by:

Blood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE ε4-enriched cognitively unimpaired elderly (2024)

Alzheimer's Research and Therapy
Koivumäki Mikko, Ekblad Laura, Lantero-Rodriguez Juan, Ashton Nicholas J., Karikari Thomas K., Helin Semi, Parkkola Riitta, Lötjönen Jyrki, Zetterberg Henrik, Blennow Kaj, Rinne Juha O., Snellman Anniina
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly (2023)

Alzheimer's Research and Therapy
Snellman Anniina, Ekblad Laura L., Tuisku Jouni, Koivumäki Mikko, Ashton Nicholas J., Lantero-Rodriguez Juan, Karikari Thomas K., Helin Semi, Bucci Marco, Löyttyniemi Eliisa, Parkkola Riitta, Karrasch Mira, Schöll Michael, Zetterberg Henrik, Blennow Kaj, Rinne Juha O.
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Head-to-head comparison of plasma p-tau181, p-tau231 and glial fibrillary acidic protein in clinically unimpaired elderly with three levels of APOE4-related risk for Alzheimer's disease (2023)

Neurobiology of Disease
Snellman Anniina, Ekblad Laura L., Ashton Nicholas J., Karikari Thomas K., Lantero-Rodriguez Juan, Pietilä Elina, Koivumäki Mikko, Helin Semi, Karrasch Mira, Zetterberg Henrik, Blennow Kaj, Rinne Juha O.
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

ASIC-E4: Interplay of Beta-Amyloid, Synaptic Density and Neuroinflammation in Cognitively Normal Volunteers With Three Levels of Genetic Risk for Late-Onset Alzheimer's Disease - Study Protocol and Baseline Characteristics (2022)

Frontiers in Neurology
Snellman Anniina, Ekblad Laura L, Koivumäki Mikko, Lindgren Noora, Tuisku Jouni, Perälä Merja, Kallio Lila, Lehtonen Riina, Saunavaara Virva, Saunavaara Jani, Oikonen Vesa, Aarnio Richard, Löyttyniemi Eliisa, Parkkola Riitta Karrasch Mira, Zetterberg Henrik, Blennow Kaj, Rinne Juha O
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
People search