Leena Kainulainen profile picture
Leena
Kainulainen
Docent, Paediatrics and Adolescent Medicine

Contact

Areas of expertise

paediatrics
immunodeficiency
paediatric infectious diseases
respiratory infections
rhinovirus

Biography

Docent Leena Kainulainen graduated from medical school in 1995(University of Turku) and defended her PhD theses on CVID in 2000. She received specialist licence in paediatrics in 2005 and in pediatric infectious diseases 2013 and was appointed as a docent in paediatrics in 2013 (University of Turku). She is currently working as Head of the Division of Pediatric Care in Turku University Hospital and as an immunology consultant at Department of Pediatrics and Medicine at Turku University Hospital. She participates in neonatal screening for severe immunodeficiencies.


Teaching

Docent Kainulainen has been working as a clinical lecturer in pediatrics 2004 and 2006. Currently she teaches regularly medical students and paediatric residents as a part of her clinical duties.


Research

Docent Kainulainen´s research is  focused on primary immunodeficiency. Her current research interests comprise rhinovirus infections in primary hypogammaglobulinemia patients. Clinical trial on the treatment of rhinovirus infection with pegylated interferon alfa in CVID patients is ongoing. Research project on innate immunity in autoimmune patients is ongoing. In addition, she participates in research project aiming at  evaluating immunological status in pediatric patients with neonatal cardiac surgery.


Publications

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Autoimmunity, hypogammaglobulinemia, lymphoproliferation and mycobacterial disease in patients with dominant activating mutations in STAT3 (2015)

Blood
Haapaniemi EM, Kaustio M, Rajala HL, van Adrichem AJ, Kainulainen L, Glumoff V, Doffinger R, Kuusanmäki H, Heiskanen-Kosma T, Trotta L, Chiang S, Kulmala P, Eldfors S, Katainen R, Siitonen S, Karjalainen-Lindsberg ML, Kovanen PE, Otonkoski T, Porkka K, Heiskanen K, Hänninen A, Bryceson YT, Uusitalo-Seppälä R, Saarela J, Seppänen M, Mustjoki S, Kere J
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Reactive Oxygen Species Deficiency Induces Autoimmunity with Type 1 Interferon Signature (2014)

Antioxidants and Redox Signaling
Kelkka Tiina, Kienhöfer Deborah, Hoffmann Markus, Linja Marjo, Wing Kajsa, Sareila Outi, Hultqvist Malin, Laajala Essi, Chen Zhi, Vasconcelos Julia, Neves Esmeralda, Guedes Margarida, Marques Laura, Krönke Gerhard, Helminen Merja, Kainulainen Leena, Olofsson Peter, JalkanenSirpa, Lahesmaa Riitta, Souto-Carneiro M. Margarida, Holmdahl Rikard
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
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