Mervi
Toriseva
Faculty of Medicine
Ph.D.
Links
Areas of expertise
FICAN West Cancer Centre, cancer biology
3D organotypic cell culture models
ECM
FGF
high-content screening
phenotypic screening
Biography
I currently work as a part time research coordinator at Western Finland Cancer Centre FICAN West to support communication and interaction among the various units and experts within the research network. I also work as a researcher in FICAN West Cancer Centre Laborotory in Medisiina D, 5th floor, studying H&N cancer in the research groupof Matthias Nees.
Teaching
- Practical laboratory courses: Cell culture, Cancer biology in vitro, Medical biochemistry
- Lectures: High-content screening
- Practical training: Live-cell analysis using IncuCyte system
Publications
The Notch inhibitor, FLI-06, increases the chemosensitivity of head and neck Squamous cell carcinoma cells to taxanes-based treatment (2024)
Biomedicine and Pharmacotherapy
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Assessment of targeted therapy opportunities in sinonasal cancers using patient-derived functional tumor models (2024)
Translational Oncology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
RUNX transcription factors are essential in maintaining epididymal epithelial differentiation (2024)
Cellular and Molecular Life Sciences
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing (2023)
Cancer Cell International
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer (2023)
Oncogenesis
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Evaluation of the anticancer activity of RIN-1, a Notch signaling modulator, in head and neck squamous cell carcinoma (2023)
Scientific Reports
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Increased Expression and Altered Cellular Localization of Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) Are Associated with Prostate Cancer Progression (2022)
Cancers
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Effects of FGFR inhibitors TKI258, BGJ398 and AZD4547 on breast cancer cells in 2D, 3D and tissue explant cultures (2020)
Cellular Oncology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Factors affecting intracellular delivery and release of hydrophilic versus hydrophobic cargo from mesoporous silica nanoparticles on 2D and 3D cell cultures (2018)
Pharmaceutics
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))