Olli Tenovuo profile picture
Professor, Clinical Neurosciences
MD, PhD, Prof. of Neurotraumatology
Pathophysiology, diagnostics, treatment, and prognosis of traumatic brain injury


Areas of expertise

traumatic brain injury


I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 40 researchers, 21 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.


Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.


The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.


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Characteristics, management and outcomes of patients with severe traumatic brain injury in Victoria, Australia compared to United Kingdom and Europe: A comparison between two harmonised prospective cohort studies (2021)

Wiegers Eveline JA, Trapani Tony, Gabbe Belinda J, Gantner Dashiell, Lecky Fiona, Maas Andrew IR, Menon David K, Murray Lynette, Rosenfeld Jeffrey V, Vallance Shirley, Lingsma Hester F, Steyerberg Ewout W, Cooper D James; and the CENTER-TBI and OzENTER-TBI investigators and participants
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Potential of heart fatty-acid binding protein, neurofilament light, interleukin-10 and S100 calcium-binding protein B in the acute diagnostics and severity assessment of traumatic brain injury (2021)

Emergency Medicine Journal
Koivikko Pia, Posti Jussi P., Mohammadian Mehrbod, Lagerstedt Linnea, Azurmendi Leire, Hossain Iftakher, Katila Ari J., Menon David, Newcombe Virginia F. J., Hutchinson Peter John, Maanpaa Henna-Riikka, Tallus Jussi, Zetterberg Henrik, Blennow Kaj, Tenovuo Olli, Sanchez Jean-Charles, Takala Riikka S. K.
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Acute Kidney Injury in Traumatic Brain Injury Patients: Results From the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study (2021)

Critical Care Medicine
Robba Chiara, Banzato Erika, Rebora Paola, Iaquaniello Carolina, Huang Chao-Yuan, Wiegers Eveline JA, Meyfroidt Geert, Citerio Giuseppe; for The Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) ICU Participants and Investigators
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)