Suomeksi
 
 
Good Laboratory Practice



KEK GLP Certificate 2018.pdfKEK GLP Certificate 2018.pdf

 

The OECD Guidelines for the testing of chemicals are followed in the Central Animal Laboratory to assess the safety of chemical products. OECD principles are approved by GLP authorities as the most relevant internationally agreed testing methods.
According to GLP rules, all actions that take place in the Central Animal Laboratory (procedures in the facilities, documentation and archiving of activities) are described in details in SOPs (Standard Operating Procedure).
The facilities are routinely inspected by authorities from Finnish Medicines Agency (Fimea) according to the national GLP Compliance Monitoring Programme, approximately every second year or more often. The main reason is to ensure that the operating instructions are put into practice.
List of OECD tests currently available
Test No. 401: Acute Oral ToxicityTest No. 402: Acute Dermal Toxicity
Test No. 404: Acute Dermal Irritation/Corrosion
Test No. 405: Acute Eye Irritation/Corrosion
Test No. 406: Skin Sensitisation
Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents
Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents
Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study
Test No. 411: Subchronic Dermal Toxicity: 90-day Study
Test No 414: Prenatal Developmental Toxicity Study
Test No. 417: Toxicokinetics
Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure
Test No. 423: Acute Oral Toxicity - Acute Toxic Class Method
Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure
Test No. 429: Skin Sensitisation: Local Lymph Node Assay
Test No. 452: Chronic Toxicity Studies
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