The Department of Clinical Neurosciences at University of Turku is committed to clinical neurological and neurosurgical education, contributing to high-level neuroscientific knowledge, and caring for patients through Neurocenter at Turku University Hospital.
Welcome to the Department of Clinical Neurosciences
The Department of Clinical Neurosciences at University of Turku is one of the leading Finnish academic centers dedicated to excellence in patient care, research and education.
Multiple clinical neurological and neurosurgical trials provide patients and their families with unique opportunities for treatment today and advance our care for the patients of tomorrow.
Internationally distinguished researchers supervise the research at the Department, and the network of professionals participating in the clinical research is extensive.
Turku PET Centre, which functions in connection with the University and Turku University Hospital, provides exceptional possibilities for neurological research.
Turku Brain and Mind Center (TBMC) gathers more than twenty neuroscience research groups in Turku
Clinical Neurosciences
Faculty of Medicine, University of Turku
Publications, Dissertations and Professors
Scientific publications
Year Publications
2013 43
2014 63
2015 81
2016 59
2017 79
2018 76
2019 86
2020 129
2021 92
2022 93
2023 78
Best Scientific Article of the Year - Winners
2022
Joutsa J, Moussawi K, Siddiqi SH, Abdolahi A, Drew W, Cohen AL, Ross TJ, Deshpande HU, Wang HZ, Bruss J, Stein EA, Volkow ND, Grafman JH, van Wijngaarden E, Boes AD, Fox MD. Brain lesions disrupting addiction map to a common human brain circuit. Nat Med 2022; 28:1249-1255
2023
Saraste M, Matilainen M, Vuorimaa A, Laaksonen S, Sucksdorff M, Leppert D, Kuhle J, Airas L. Association of serum neurofilament light chain with microglial activation in multiple sclerosis. J Neurol Neurosurg Psychiatry 2023; 94:698-706
Doctoral Dissertations
- Panelius, Martin. 1969. Studies on epidemiological, clinical and etiological aspects of multiple sclerosis.
- Frey, Harri. 1971. Enzymes of central nervous system myelin with special reference to maturation. An experimental study on guinea pigs.
- Sonninen, Vesa. 1971. Clinical, experimental and biochemical studies on the significance of monoamines in Parkinson's disease.
- Lehtonen, Johannes. 1972. Visual evoked cortical potentials in man. Studies on recording and stimulation technique, and findings in migraine patients.
- Marttila, Reijo. 1974. Epidemiological, clinical, and virus-serological studies of Parkinson's disease.
- Siirtola, Taisto. 1974. Long-term treatment of Parkinson's disease with levodopa. Clinical and metabolic studies.
- Kalimo, Hannu. 1974. Ultrastructural studies on the hypothalamic neurosecretory neurons of the rat.
- Kangasniemi, Pentti. 1975. Biogenic amines and vasoactive peptides in the pathophysiology of migraine. Biochemical, clinical and therapeutical correlations
- Kytömäki, Ossi. 1975. Hypothalamic-pituitary-adrenal function in patients with intracranial neurological diseases
- Nikoskelainen, Eeva. 1975. Clinical, prognostic and etiological studies on optic neuritis. With special reference to its relationship to multiple sclerosis
- Molnár, Gábor. 1976. Experimental allergic neuritis. Immunological, neurochemical and morphological studies on rabbits
- Laaksonen, Hannu. 1977. Brain dopamine, GABA and acetylcholine neurons in the pathophysiology of Parkinson's disease. Neurochemical, clinical and therapeutical correlations
- Rautakorpi, Ilkka. 1978. Essential tremor. An epidemiological, clinical and genetic study
- Pynnönen, Seppo. 1979. Studies in the determination and the clinical pharmacokinetics of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients, alcoholics and controls
- Röyttä, Matias. 1979. Studies on the pathogenesis of multiple sclerosis. Morphological and neurochemical aspects
- Narva, Erkki. 1980. Radionuclide brain scanning and rapid sequential scintiphotography in patients with cerebral infarction
- Mölsä, Pekka. 1980. Dementia. A clinical study in the Finnish population
- Hukkanen, Veijo. 1982. Glycoprotein antigens in multiple sclerosis
- Saksa, Markku. 1982. The autonomic nervous system in experimental allergic neuritis. A functional, morphological and biochemical study
- Halonen, Jukka-Pekka. 1982. Normal and pathological firing pattern of single motor units in man
- Salonen, Reijo. 1983. Interferons in multiple sclerosis and optic neuritis
- Ruutiainen, Juhani. 1983. Studies on antibodies to central nervous system dominant antigens. With special reference to multiple sclerosis.
- Laihinen, Arto. 1983. Dopamine receptor function in Parkinson's disease. A clinical and biochemical study
- Forssell, Heli. 1985. Mandibular dysfunction and headache
- Grénman, Reidar. 1985. Involvement of the audiovestibular system in multiple sclerosis. An otoneurological and audiological study
- Halonen, Päivi. 1986. Vibratory perception thresholds in healthy and neurologically affected adults and children
- Koski, Kari. 1987. Threatened stroke. A clinical study of risk factors, atherosclerosis, role of platelet aggregation, and outcome in transient ischemic attacks and relation to transient global amnesia
- Rinne, Juha. 1987. Alzheimer's disease, vascular dementia and aging. A study of brain cholinergic and dopaminergic receptors with neuropathological aspects
- Laine, Matti. 1989. On the mechanisms of verbal adynamia. A neuropsychological study
- Nyrke, Timo. 1991. Spectral analysis of steady-state visual evoked potentials and the alpha rhythm in migraine
- Tenovuo, Olli. 1992. Substance P in Parkinson's disease, Alzheimer's disease and ageing
- Kotilainen, Esa. 1994. Microinvasive lumbar disc surgery: a study on patients treated with microdiscectomy or percutaneous nucleotomy for disc herniation
- Heinonen, Esa. 1995. Selegiline in the treatment of Parkinson's disease. Pharmacokinetic and clinical studies
- Päivärinta, Markku. 1995. Motor behaviour in experimental herpes simplex virus brain infection. Responses in dopamine and serotonin systems
- Soilu-Hänninen, Merja. 1996. Viruses and autoimmune inflammation in the brain: Role of leukocyte and endothelial cell adhesion molecules
- Ma, Shuang Yong. 1997. The substantia nigra in Parkinson's disease. A morphometric study on neuronal changes
- Erälinna, Juha-Pekka. 1997. Viral Facilitation and Treatment of Experimental Allergic Encephalomyelitis in Balb/c Mice
- Ruottinen, Hanna. 1998. Catechol-O-methyltransferase inhibition in the treatment of Parkinson's disease. Responses to entacapone in positron emission tomography, pharmacokinetic and clinical studies
- Mattila, Petri. 1999. Cortical Lewy bodies and Alzheimer-type pathology in Parkinson's disease in relatation to cognitive impairment. A neuropathological and biochemical study
- Kaasinen, Valtteri. 2000. Dopamine D2-like receptors in the human brain. Positron emission tomography studies in Parkinson's disease and in healthy subjects
- Kaarisalo, Minna. 2000. Stroke and heart. Epidemiological studies on relations between stroke and cardiac disorders
- Portin, Raija. 2000. Cognitive functioning in midlife. Assessment by mild deterioration battery and CogniSpeed
- Lamusuo, Salla. 2001. Imaging the epileptogenic region with positron emission tomography in patients with temporal lobe epilepsy
- Nurmi, Elina. 2001. Progression of nigrostriatal hypofunction in Parkinson's disease
- Kemppainen, Nina. 2002. Brain dopamine transporter and receptors in Alzheimer's disease
- Järvenpää, Tarja. 2003. Monozygotic twins and cognitive decline with emphasis on Alzheimer's disease
- Laatu, Sari. 2003. Semantic memory deficits in Alzheimer's disease, Parkinson's disease and multiple sclerosis
- Brück, Anna. 2005. Cognitive impairment in early Parkinson's disease. A positron emission tomography and magnetic resonance imaging study
- Roine, Susanna. 2005. Clinical and imaging findings in CADASIL
- Kupila, Laura. 2005. Aetiological diagnosis of acute central nervous system infections in adults. The role of PCR
- Koponen, Salla. 2006. Psychiatric sequelae of traumatic brain injury
- Strandberg, Marjatta. 2007. The role of transesophageal echocardiography in patients with ischemic stroke, transient ischemic attack, or atrial fibrillation
- Hiekkanen, Heli. 2009. Apolipoprotein E and Recovery from Traumatic Brain Injury
- Koivunen, Jaana. 2011. Mild Cognitive Impairment and Early Detection of Alzheimer`s Disease. A Positron Emission Tomography Study
- Jokinen, Pekka. 2011. PET and MR imaging in Parkinson’s disease patients with cognitive impairment. A study of dopaminergic dysfunction, amyloid deposition, cortical hypometabolism and brain atrophy
- Himanen, Leena. 2011. Cognitive Functions After Traumatic Brain Injury. A 30-year Follow-up Study
- Martikainen, Mika. 2012. Mitochondrial disease in Southwestern Finland. Population-based molecular genetic and clinical studies
- Virta, Jyri. 2012. Genetically Determined Hypometabolism in Alzheimer’s Disease and Midlife Risk Factors for Cognitive Impairment
- Joutsa, Juho. 2012. Neurobiology of pathological gambling. Brain imaging and epidemiological studies
- Frantzén, Janek. 2012. Bioactive Glass in Lumbar Spondylodesis. A Pre-Clinical and Clinical Study
- Posti, Jussi. 2012. Alpha2-Adrenoceptor-mediated vascular responses induced by dexmedetomidine
- Lindroos, Markus. 2013. On Glucose Metabolism in Patients with the m.3243A>G Mutation
- Puustinen, Juha. 2014. Benzodiazepines and Cognitive Functioning in Older Adults. With Emphasis on Long-Term Use and Withdrawal
- Jalkanen, Anna. 2014. Multiple sclerosis and pregnancy: clinical and immunological aspects
- Jokela, Manu. 2015. Late-onset spinal motor neuronopathy- a new neuromuscular disease
- Tuulari, Jetro. 2015. Effects of Obesity and Weight Loss Following Bariatric Surgery on Brain Function, Structural Integrity and Metabolism
- Rissanen, Eero. 2015. Imaging Neuroinflammation in Progressive Multiple Sclerosis
- Koskimäki, Janne. 2015. Intracranial Nimodipine Implant: Feasibility and Implications for the Treatment of Subarachnoid Hemorrhage – A Pre-Clinical Study
- Karlsson, Henry. 2016. Neuroreceptor availability and cerebral morphology in human obesity
- Åivo, Julia. 2017. Vitamin D in the Prevention and Treatment of Multiple Sclerosis
- Lindholm, Pauliina. 2017. Neural mechanisms of orofacial pain - effects of transcranial magnetic stimulation
- Sipilä, Jussi. 2017. Huntington’s disease in Finland. Epidemiologic, genetic and clinical studies
- Saraste, Maija. 2018. Pregnancy-related immune alterations in multiple sclerosis
- Mäkinen, Elina. 2018. Diagnostic and prognostic aspects of clinical brain dopamine transporter imaging in parkinsonism
- Saarenpää, Ilkka. 2018. Factors affecting accuracy and fusion rate in lumbosacral fusion surgery - a preclinical and clinical study
- Sihvonen, Aleksi. 2018. Neural basis of acquired amusia and its recovery
- Jaakkola, Elina. 2018. Neuropsychiatric symptoms and brain dopamine transporter imaging in Parkinson's disease
- Majuri, Joonas. 2019. Dopamine, opioid and serotonin neurotransmission in behavioral addictions
- Östberg, Anna. 2019. Cholinergic system in sequelae of traumatic brain injury
- Sahlsten, Hanna. 2019. Tinnitus – psychiatric comorbidity and treatment using transcranial magnetic stimulation (TMS)
- Åkerlund, Kira. 2020. Environmental and lifestyle factors in multiple sclerosis with emphasis on vitamin D, EBV infection, smoking and cancer risk
- Hossain, Iftakher. 2020. Acute biochemical diagnostics of mild traumatic brain injury : A clinical study
- Kuusimäki, Tomi. 2021. Phenotype-, comorbidity-, and treatment-related prognostic factors in Parkinson’s disease
- Lindgrén, Noora. 2021. Early detection of Alzheimer’s disease - Twin study on episodic memory and imaging biomarkers of neuroinflammation and β-amyloid
- Tuisku, Jouni. 2021. Imaging of neuroinflammation in multiple sclerosis brain : a positron emission tomography and diffusion tensor imaging study
- Pirttisalo, Anna-Leena. 2021. Epidemiology of multiple sclerosis in Finland with the emphasis on hospitalization and infection-related admissions
- Mohammadian, Mehrbod. 2021. Microstructural analysis of diffuse axonal injury after traumatic brain injury using diffusion-weighted Magnetic resonance imaging
- Kotkansalo, Anna. 2022. Surgery for degenerative and rheumatoid cervical spine disease in Finland
- Vainio, Susanne. 2022. Experimental models of focal neuroinflammation - Efficacy assessment of pharmaceuticals of multiple sclerosis using PET imaging
- Honkanen, Emma. 2022. Basal ganglia function in parkinsonism and dystonia
- Kuutti, Katariina. 2022. Early prognostic factors of multiple sclerosis
- Kantonen, Tatu. 2022. Brain opioid and endocannabinoid systems as risk factors for obesity. Positron emission tomography studies of μ-opioid and CB1 receptors with glucose uptake analysis
- Saari, Laura. 2022. Clinicopathological characteristics of nigral neuron density in Lewy body spectrum diseases
- Malmberg-Ceder, Kirsi. 2022. Pain in Finnish female municipal employees with special reference to psychosocial and work-related factors and quality of life
- Laukka, Dan. 2023. Intracranial aneurysms in patients with Kawasaki disease or thoracic aortic aneurysms
Adjunct Professors (Docents)
- Marttila Reijo, experimental neurology, 1977
- Valtonen Simo, neurosurgery,1983
- Molnar Gabor, neurology, 1987
- Mölsä Pekka, neurology,1987
- Laihinen Arto, neurology, 1989
- Rinne Juha, neurology, 1996
- Ruutiainen Juhani, neurology, 1998
- Kotilainen Esa, neurosurgery, 1999
- Ruottinen Hanna, neurology, 2000
- Elovaara Irina, neurology, 2001
- Vuorinen Ville, neurosurgery, 2004
- Kaasinen Valtteri, experimental neurology, 2005
- Kuoppamäki Mikko, neurology, 2005
- Tenovuo Olli, neurology, 2005
- Airas Laura, neurology, 2007
- Soilu-Hänninen Merja, neurology, 2008
- Majamaa Kari, neurology, 2009
- Martikainen Mika, neurology, 2014
- Joutsa Juho, experimental neurology, 2015
- Kivelev Juri, neurosurgery, 2016
- Posti Jussi, neurosurgery, 2017
- Frantzen Janek, neurosurgery, 2017
- Bogoslovsky Tanya, neurology, 2017
- Sipilä Jussi, neurology, 2018
- Puustinen Juha, neurology, 2019
- Jokela Manu, neurology, 2020
- Tarvonen-Schröder Sinikka, neurology, 2020
- Koskimäki Janne, experimental neurosurgery, 2020
- Ruuskanen Jori, neurology, 2021
- Rissanen Eero, neurology, 2021
- Rahi Melissa, neurosurgery, 2022
- Honkaniemi Jari, neurology, 2022
- Brück Anna, neurology, 2023
Professors
- Rinne Urpo, professor of neurology, 1969-2000
- Riekkinen Paavo, associate professor of neurology, 1973-1979
- Panelius Martin, associate professor of neurology,1979-1997
- Marttila Reijo, professor of neurology, 2002-2009
- Majamaa Kari, professor of neurology, 2005-2008
- Roine Risto O., professor of neurology, 2010-2021
- Soinila Seppo, professor of neurology, 2011-2020
- Rinne Jaakko, professor of neurosurgery, 2016-ongoing
- Airas Laura, professor of neuroimmunology, 2017-ongoing
- Tenovuo Olli, professor of neurotraumatology, 2019-ongoing
- Martikainen Mika, associate professor of neurology, 2021-2022
- Honkaniemi Jari, associate professor of neurology, 2021-ongoing
- Kaasinen Valtteri, professor of neurology, 2021-ongoing
- Joutsa Juho, professor of neurology, 2023-ongoing
Recent publications
Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS) (2024)
World Journal of Emergency Surgery
(Article or data-article in scientific journal (B1))
Consensus-based recommendations for diagnosis and surgical management of cranioplasty and post-traumatic hydrocephalus from a European panel (2024)
Brain and Spine
(Refereed journal article or data article (A1))
Low and Borderline Ankle-Brachial Index Is Associated With Intracranial Aneurysms: A Retrospective Cohort Study (2024)
Neurosurgery
(Refereed journal article or data article (A1))
