Frontiers of Science: Prof. Marco Foiani: Connecting cell metabolism with DNA Damage Response

Prof. Marco Foiani, IFOM, The FIRC Institute of Molecular Oncology & University of Milan, Italy:
Connecting cell metabolism with DNA Damage Response

Host: Jukka Westermarck (

Marco Foiani is Professor of Molecular Biology at the University of Milan and, since 2009, Scientific Director of IFOM, an international cancer center that hosts 20 groups and 300 scientists. Prof. Foiani has studied different cellular processes (translational, chromosome replication, DNA recombination, DNA repair, DNA topology, tranion, autophagy and nuclear envelope dynamics) and regulatory pathways (translational control, cell cycle, checkpoint, sumo and ubiquitin pathways, protein acetylation, gene gating) using a variety of approaches (biochemical, genetic, imaging, genomic, molecular biology). His major contributions are within the fields of chromosome dynamics and genome integrity. His work has contributed to elucidate the ATR and ATM-dependent checkpoint processes controlling the interfaces between DNA replication, recombination, tranion and DNA topology and preventing abnormal chromosome transitions.
Terhi Jokilehto