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Valikoituja julkaisuja


Yatkin E, Polari L, Laajala T, Smeds A, Eckerman C, Holmbom B, Saarinen N, Aittokallio T, Mäkelä S. Novel Lignan and stilbenoid mixture shows anticarcinogenic efficacy in preclinical PC-3M-luc2 prostate cancer model. PLoS One. 9:e93764, 2014

Strauss L, Rantakari P, Sjögren K, Salminen A, Lauren E, Kallio J, Damdimopoulou P, Boström M, Boström PJ, Pakarinen P, Zhang F, Kujala P, Ohlsson C, Mäkelä S, Poutanen M: Seminal vesicles and urinary bladder as sites of aromatization of androgens in men, evidenced by a CYP19A1-driven luciferase reporter mouse and human tissue specimens. FASEB J 27: 1342-1350, 2013

Polari L, Ojansivu P, Mäkelä S, Eckerman C, Holmbom B, Salminen S. Galactoglucomannan extracted from spruce (Picea abies) as a carbohydrate source for probiotic bacteria. J Agric Food Chem 60:11037-11043, 2012

Damdimopoulou P, Nurmi T, Salminen A, Damdimopoulos AE, Kotka M, van der Saag P, Strauss L, Poutanen M, Pongratz I, Mäkelä S. A single dose of enterolactone activates estrogen signaling and regulates expression of circadian clock genes in mice. J Nutr 141:1583-9, 2011

Lindahl G, Saarinen N, Abrahamsson A, Dabrosin C. Tamoxifen, Flaxseed, and the Lignan Enterolactone Increase Stroma- and Cancer Cell–Derived IL-1Ra and Decrease Tumor Angiogenesis in Estrogen-Dependent Breast Cancer. Cancer Res 71:51-60, 2011

Saarinen N, Abrahamsson A, Dabrosin C. Estrogen-induced angiogenic factors derived from stromal and cancer cells are differently regulated by enterolactone and genistein in human breast cancer in vivo. Int J Cancer. 127:737-745, 2010

Penttinen-Damdimopoulou PE, Power KA, Hurmerinta TT, Nurmi T, van der Saag PT, Mäkelä S. Dietary sources of lignans and isoflavones modulate responses to estradiol in estrogen reporter mice. Mol Nutr Food Res 53:996-1006, 2009

Saarinen NM, Wärri A, Dings RPM, Airio M, Smeds AI, Mäkelä S. Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats. Int J Cancer 123:1196-1204, 2008

Warri A, Saarinen NM, Mäkelä S, Hilakivi-Clarke L. The role of early life genistein exposures in modifying breast cancer risk. Br J Cancer 98:1485-1493, 2008

Penttinen P, Jaehrling, J, Damdimopoulos AE, Inzunza J, Lemmen, JG, van der Saag P, Pettersson K, Gauglitz G, Mäkelä S, Pongratz I. Diet-derived polyphenol metabolite enterolactone is a tissue-specific estrogen receptor activator. Endocrinology 148:4875-4876, 2007

Saarinen NM, Wärri A, Airio M, Smeds A, Mäkelä S. Role of dietary lignans in the reduction of breast cancer risk. Mol Nutr Food Res 51:857-866, 2007.