Shruti Jain profile picture

Shruti
Jain

Biotechnology
Postdoctoral researcher
Early Cancer Diagnostics group, FICAN West Cancer Centre, InFLAMES Flagship

Contact

+358 29 450 4599
+358 50 573 8984
Kiinamyllynkatu 10
20520
Turku

Areas of expertise

Diagnostics
immunoassays
point-of-care testing
assay optimization
clinical validation
clinical verification
analytical techniques
biomarkers
tumor markers
extracellular vesicle (EV) diagnostics
clinical chemistry
laboratory medicine
statistical analysis, SPSS, Origin, JMP, R programming
science communication

Biography

I am a Postdoctoral researcher in the Biotechnology unit at the Department of Life Technologies. My current research is on clinical biomarkers and epidemiological studies in lung cancer. 

I have extensive experience in immunoassay development and optimization, along with verification and clinical validation studies. I have also done extensive data analysis and am experienced with using R programming, SPSS, Origin, JMP. I also have some knowledge regarding regulatory considerations. 

Research

Cancer is largely asymptomatic in early stages and the mortality increases with late detection. I look at glycosylation changes in cancer to identify new biomarkers that can be used as diagnostic targets. We have a highly sensitive and fluorescent nanoparticle based technology that we use to develop diagnostic assays for early cancer detection. I have developed an ovarian cancer diagnostic test that shows improved performance in postmenopausal women and in early stage cases compared to conventional assays. This test is now in the commercialization phase with a local diagnostic Turku based company. My current research as a postdoc includes identifying novel biomarkers for lung cancer diagnosis, that we are now in the process of patenting. 

Publications

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Novel glycovariant biomarkers of CA125 and CA15-3 and their diagnostic performance across histotypes of ovarian cancer: A multi-cohort study in Sweden and Finland (2025)

European Journal of Obstetrics and Gynecology and Reproductive Biology
Roos Alexander, Hanna; Jain, Shruti; Gidwani, Kamlesh; Ulfenborg, Benjamin; Ottander, Ulrika; Lundin, Eva; Hynninen, Johanna; Afrin Ruma, Shamima; Huhtinen, Kaisa; Sundfeldt, Karin; Pettersson, Kim; Idahl, Annika
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )