Jorma Toppari profile picture
Jorma
Toppari
InFLAMES Flagship
Professor, Institute of Biomedicine
MD, PhD

Contact

+358 29 450 2826
+358 40 180 2600
Kiinamyllynkatu 10
20520
Turku

Links

Publications J Toppari 2018 Nov.pdf
CV_Jorma_Toppari_ 2018_Nov.pdf
ORCID

Areas of expertise

Pediatric endocrinology
reproductive health
endocrine disruption
testis
type 1 diabetes

Biography

Professor Jorma Toppari (H-index 68) is an international expert in environmental endocrine disruption, male reproduction and type 1 diabetes. He is a principal investigator in a NIH-funded cohort study The Environmental Determinants of Diabetes in the Young (TEDDY) and in the Finnish Type 1 Diabetes Prediction and Prevention Study (DIPP). He is leading a joint Finnish-Danish birth cohort study exploring the genetic and environmental aspects of human reproduction. 

Teaching

Basic and clinical endocrinology, particularly pediatric and reproductive endocrinology, endocrine disruption, reproductive toxicology

Research

The aim of our research is to identify risk factors of reproductive health and type 1 diabetes (T1D) to make risk management possible and prevent health problems. We are performing a comprehensive reproductive health study for 19-year-old men that we have followed up prospectively from pregnancy. We focus now our studies on sperm epigenome. We are studying the role of retinoblastoma protein (Rb) and E2F3 transcription factors in gonadal development and whether endocrine disruptors affect reproductive health. In the Finnish type 1 Diabetes Prediction and Prevention (DIPP) study and in The Environmental Determinants of Diabetes in the Young (TEDDY) study we are exploring the early determinants of T1D in large child cohorts with increased genetic risk.

Publications

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HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children (2022)

Pediatric Diabetes
Salami Falastin, Tamura Roy, You Lu, Lernmark Åke, Larsson Helena Elding, Lundgren Markus, Krischer Jeffrey, Ziegler Anette-Gabriele, Toppari Jorma, Veijola Riitta, Rewers Marian, Haller Michael J., Hagopian William, Akolkar Beena, Törn Carina; TEDDY Study Group
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

RUBIC (ReproUnion Biobank and Infertility Cohort): A binational clinical foundation to study risk factors, life course, and treatment of infertility and infertility-related morbidity (2021)

Andrology
Priskorn Lærke, Tøttenborg Sandra Søgaard, Almstrup Kristian, Andersson Anna-Maria, Axelsson Jonatan, Bräuner Elvira Vaclavik, Elenkov Angel, Freiesleben Nina la Cour, Giwercman Yvonne Lundberg, Grøndahl Marie Louise, Hansen Ann Holm, Hansen Laura Smidt, Henic Emir, Kitlinski Margareta Laczna, Landersoe Selma Kloeve, Lindh Christian, Løkkegaard Ellen Leth, Malm Johan, Olsen Kristina Wendelboe, Petersen Kajsa Uglevig, Schmidt Lone, Stormlund Sacha, Svendsen Pernille Fog, Vassard Ditte, Wang Nathalie Friis, Zedeler Anne, Bhasin Shalender, Chavarro Jorge, Eisenberg Michael L., Hauser Russ, Huhtaniemi Ilpo, Krawetz Stephen A., Marko-Varga György, Salonia Andrea, Toppari Jorma, Juul Anders, Jørgensen Niels, Nielsen Henriette Svarre, Pinborg Anja, Rylander Lars, Giwercman Aleksander
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) study (2021)

American Journal of Clinical Nutrition
Hummel Sandra, Weiss Andreas, Bonifacio Ezio, Agardh Daniel, Akolkar Beena, Aronsson Carin A, Hagopian William A, Koletzko Sibylle, Krischer Jeffrey P, Lernmark Ake, Lynch Kristian, Norris Jill M, Rewers Marian J, She Jin-Xiong, Toppari Jorma, Uusitalo Ulla, Vehik Kendra, Virtanen Suvi M, Beyerlein Andreas, Ziegler Anette-G
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Placenta is Capable of Protecting the Male Fetus from Exposure to Environmental Bisphenol A (2021)

Exposure and Health
Lukasiewicz Monika, Czerniecki Jan, Ponikwicka-Tyszko Donata, Sztachelska Maria, Hryniewicka Marta, Nalewajko-Sieliwoniuk Edyta, Wiczkowski Wieslaw, Banaszewska Beata, Milewski Robert, Toppari Jorma, Huhtaniemi Ilpo, Rahman Nafis A., Wolczynski Slawomir
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Sukupuolen kehityksen biologia ja genetiikka (2021)

Duodecim
Kohva Ella, Holopainen Elina, Huopio Hanna, Keskinen Päivi, Ojaniemi Marja, Taskinen Seppo, Toppari Jorma, Raivio Taneli, Miettinen Päivi J
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))
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