Jorma Toppari profile picture
Jorma
Toppari
InFLAMES Flagship
Professor, Institute of Biomedicine
MD, PhD

Contact

+358 29 450 2826
+358 40 180 2600
Kiinamyllynkatu 10
20520
Turku

Links

Publications J Toppari 2018 Nov.pdf
CV_Jorma_Toppari_ 2018_Nov.pdf
ORCID

Areas of expertise

Pediatric endocrinology
reproductive health
endocrine disruption
testis
type 1 diabetes

Biography

Professor Jorma Toppari (H-index 68) is an international expert in environmental endocrine disruption, male reproduction and type 1 diabetes. He is a principal investigator in a NIH-funded cohort study The Environmental Determinants of Diabetes in the Young (TEDDY) and in the Finnish Type 1 Diabetes Prediction and Prevention Study (DIPP). He is leading a joint Finnish-Danish birth cohort study exploring the genetic and environmental aspects of human reproduction. 

Teaching

Basic and clinical endocrinology, particularly pediatric and reproductive endocrinology, endocrine disruption, reproductive toxicology

Research

The aim of our research is to identify risk factors of reproductive health and type 1 diabetes (T1D) to make risk management possible and prevent health problems. We are performing a comprehensive reproductive health study for 19-year-old men that we have followed up prospectively from pregnancy. We focus now our studies on sperm epigenome. We are studying the role of retinoblastoma protein (Rb) and E2F3 transcription factors in gonadal development and whether endocrine disruptors affect reproductive health. In the Finnish type 1 Diabetes Prediction and Prevention (DIPP) study and in The Environmental Determinants of Diabetes in the Young (TEDDY) study we are exploring the early determinants of T1D in large child cohorts with increased genetic risk.

Publications

Sort by:

RANKL regulates male reproductive function (2021)

Nature Communications
Jensen MB, Andreassen CH, Jorgensen A, Nielsen JE, Mortensen L, Boisen IM, Schwarz P, Toppari J, Baron R, Lanske B, Juul A
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Land Cover of Early-Life Environment Modulates the Risk of Type 1 Diabetes (2021)

Diabetes Care
Nurminen Noora, Cerrone Damiano, Lehtonen Jussi, Parajuli Anirudra, Roslund Marja, Lonnrot Maria, Ilonen Jorma, Toppari Jorma, Veijola Riitta, Knip Mikael, Rajaniemi Juho, Laitinen Olli H., Sinkkonen Aki, Hyöty Heikki
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

TEDDY luo toivoa (2021)

Diabetes ja lääkäri
Toppari Jorma, Knip Mikael, Kurppa Kalle, Hyöty Heikki, Ilonen Jorma, Veijola Riitta, Virtanen Suvi M.
(Artikkeli ammattilehdessä tai kirjoitus ammatillisessa blogissa (D1))

Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the US (2021)

Diabetes Care
Anand Vibha, Li Ying, Liu Bin, Ghalwash Mohamed, Koski Eileen, Ng Kenney, Dunne Jessica L., Jonsson Josefine, Winkler Christiane, Knip Mikael, Toppari Jorma, Ilonen Jorma, Killian Michael B., Frohnert Brigitte I., Lundgren Markus, Ziegler Anette-Gabriele, Hagopian William, Veijola Riitta, Rewers Marian; for the T1DI Study Group
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
People search