Juhani
Knuuti
Director, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Myocardial glucose uptake is enhanced in essential hypertension induced left ventricular hypertrophy (1997)
Scandinavian Cardiovascular Journal Supplements
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Comparison of[18F]FDG-PET, [99mTc]-HMPAO-SPECT, and [123I]-iomazenil-SPECT in localising the epileptogenic cortex (1997)
Journal of Neurology, Neurosurgery and Psychiatry
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Myocardial efficiency during calcium sensitization with levosimendan: A noninvasive study with positron emission tomography and echocardiography in healthy volunteers (1997)
Clinical Pharmacology and Therapeutics
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Fatty acid uptake is preserved in chronically dysfunctional but viable myocardium (1997)
American journal of physiology : heart and circulatory physiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Effects of insulin on blood flow and volume in skeletal muscle of patients with IDDM: Studies using [15O]H20, [15O]CO, and positron emission tomography (1997)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Acute effects of celiprolol on muscle blood flow and insulin sensitivity: Studies using [15O]-water, [18F]-fluorodeoxyglucose and positron emission tomography (1997)
European Journal of Clinical Pharmacology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Myocardial glucose uptake in patients with NIDDM and stable coronary artery disease (1997)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Role of blood flow in regulating insulin-stimulated glucose uptake in humans: Studies using bradykinin, [15O]water, and [18F]Fluoro-deoxy-glucose and positron emission tomography (1996)
Journal of Clinical Investigation
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Effect of left internal thoracic artery dissection on sternal vascularization (1996)
Scandinavian journal of thoracic and cardiovascular surgery
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Evidence for dissociation of insulin stimulation of blood flow and glucose uptake in human skeletal muscle: Studies using [15O]H2O, [118F]fluoro-2-deoxy-D-glucose, and positron emission tomography (1996)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))