Juhani
Knuuti
Director, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Current-density estimation of exercise-induced ischemia in patients with multivessel coronary artery disease (2001)
Journal of Electrocardiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Myocardial fatty acid oxidation in patients with impaired glucose tolerance (2001)
Diabetologia
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Human adipose tissue glucose uptake determined using [18F]-fluoro-deoxy-glucose ([18F]FDG) and PET in combination with microdialysis (2001)
Diabetologia
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Global myocardial blood flow and global flow reserve measurements by MRI and PET are comparable (2001)
Journal of Magnetic Resonance Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Assessing coronary sinus blood flow in patients with coronary artery disease: A comparison of phase-contrast MR imaging with positron emission tomography (2001)
American Journal of Roentgenology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Evidence for spatial heterogeneity in insulin- and exercise-induced increases in glucose uptake: studies in normal subjects and patients with type 1 diabetes (2001)
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))Multimodality MR imaging assessment of myocardial viability: Combination of first-pass and late contrast enhancement to wall motion dynamics and comparison with FDG PET - Initial experience (2000)
Radiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Impaired free fatty acid uptake in skeletal muscle but not in myocardium in patients with impaired glucose tolerance: Studies with PET and 14(R, S)- [18F]fluoro-6-thia-heptadecanoic acid (2000)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Assessment of coronary flow reserve using fast velocity-encoded cine MR imaging: Validation study using positron emission tomography (2000)
American Journal of Roentgenology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Glucose kinetics in skeletal muscle assessed by [18F]FDG PET data: a new four compartment five rate constant model (2000)
Annals of Biomedical Engineering
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))