Juhani
Knuuti
Director, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Single nucleotide polymorphisms in the peroxisome proliferator-activated receptor delta gene are associated with skeletal muscle glucose uptake (2005)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Cardiac resynchronization therapy - Part 2 - Issues during and after device (2005)
Journal of the American College of Cardiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Free Fatty Acid Biodistribution and Triglyceride Metabolism Using the Fatty Acid Analogue 18F-FTHA during Fasting and Hyperinsulinemia (2005)
European Journal of Nuclear Medicine and Molecular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Rosiglitazone improves myocardial glucose uptake in patients with type 2 diabetes and coronary artery disease - A 16-week randomized, double-blind, placebo-controlled study (2005)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Weight reduction increases skeletal muscle and adipose tissue but not myocardial insulin sensitivity. Study with positron emission tomography (2005)
Diabetologia
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology (2005)
European Journal of Nuclear Medicine and Molecular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Insulin improves myocardial blood flow in patients with type 2 diabetes and coronary artery disease (2005)
Journal of the American College of Cardiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
The assessment of glucose appearance rate and hepatic glucose uptake by [18F]fluorodeoxyglucose: validation against 6,6-2H-glucose (2005)
Diabetologia
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes - A positron-emitting tomography study (2005)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Rosiglitazone increases the concentration of large, buoyant but not small dense LDL in patients with type 2 diabetes and coronary artery disease, a 16 week randomised, double-blind, placebo-controlled study (2005)
Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))