Jussi Lehto

Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis (2025)

Journal of Neurology, Neurosurgery and Psychiatry

Ahola, Venla; Saraste, Maija; Nylund, Marjo; Matilainen, Markus; Luoma, Amelie; Vuorimaa, Anna; Lehto, Jussi; Laaksonen, Sini; Brockmann, Eeva-Christine; Kuhle, Jens; Leppert, David; Soukka, Tero; Lamminmäki, Urpo; Airas, Laura

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Synaptic Density in Multiple Sclerosis (2025)

Neurology, Neuroimmunology and Neuroinflammation

Luoma, Amelie; Matilainen, Markus; Tuisku, Jouni Mikael; Aarnio, Richard; Nikkilä, Taru; Laaksonen, Sini; Koivumäki, Mikko; Honkonen, Eveliina; Nylund, Marjo; Wahlroos, Saara; Solin, Olof; Chen, Ming-Kai; Toyonaga, Takuya; Lehto, Jussi; Snellman, Anniina; Rinne, Juha O.; Airas, Laura M.

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Broad rim lesions are a new pathological and imaging biomarker for rapid disease progression in multiple sclerosis (2025)

Nature Medicine

Klotz, Luisa; Smolders, Joost; Lehto, Jussi; Matilainen, Markus; Lütje, Lukas; Buchholz, Luzia; Albrecht, Stefanie; Walter, Carolin; Varghese, Julian; Wiendl, Heinz; Nylund, Marjo; Thomas, Christian; Gardberg, Maria; van den Bosch, Aletta M. R.; Airas, Laura; Huitinga, Inge; Kuhlmann, Tanja

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Longitudinal accumulation of glial activation measured by TSPO-PET predicts later brain atrophy in multiple sclerosis (2025)

Journal of Neuroinflammation

Nylund, Marjo; Lehto, Jussi; Matilainen, Markus; Rajander, Johan; Wahlroos, Saara; Sucksdorff, Marcus; Kuhlmann, Tanja; Airas, Laura

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Synaptic density in multiple sclerosis: An in vivo study using [11C]UCB-J-PET imaging (2024)

Multiple Sclerosis

Luoma, Amelie; Matilainen, Markus; Tuisku, Jouni; Aarnio, Richard; Nikkila, Taru; Laaksonen, Sini; Koivumaki, Mikko; Honkonen, Eveliina; Nylund, Marjo; Wahlroos, Saara; Toyonaga, Takuya; Chen, Ming-Kai; Lehto, Jussi; Snellman, Anniina; Rinne, Juha; Airas, Laura

(Abstrakti)

P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study (2024)

EJNMMI Research

Lehto, Jussi; Aarnio, Richard; Tuisku, Jouni; Sucksdorff, Marcus; Koivumäki, Esa Mikko; Nylund, Marjo; Helin, Semi; Rajander, Johan; Danon, Jonathan; Gilchrist, Jayson; Kassiou, Michael; Oikonen, Vesa; Airas, Laura

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

TSPO-PET-measurable microglial activity remains unaltered in cladribine-treated RRMS patients (2024)

The European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Multiple Sclerosis

Rajalehto, Olli; Saraste, Maija; Matilainen, Markus; Nylund, Marjo; Honkonen, Eveliina; Lehto, Jussi; Airas, Laura

(Konferenssiposteri)

PET-measurable innate immune cell activation reduction in chronic active lesions in PPMS brain after rituximab treatment: a case report (2023)

Journal of Neurology

Lehto Jussi, Sucksdorff Marcus, Nylund Marjo, Raitanen Roope, Matilainen Markus, Airas Laura

(B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä )

Longitudinal stability of progression-related microglial activity during teriflunomide treatment in patients with multiple sclerosis (2023)

European Journal of Neurology

Lehto Jussi, Nylund Marjo, Matilainen Markus, Sucksdorff Marcus, Vuorimaa Anna, Rajander Johan, Wahlroos Saara, Hariri Parisa, Laura Airas

(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

The alpha2C-adrenoceptor as a neuropsychiatric drug tar-get - PET studies in human subjects (2015)

Lehto Jussi

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Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis (2025)

Synaptic Density in Multiple Sclerosis (2025)

Broad rim lesions are a new pathological and imaging biomarker for rapid disease progression in multiple sclerosis (2025)

Longitudinal accumulation of glial activation measured by TSPO-PET predicts later brain atrophy in multiple sclerosis (2025)

Synaptic density in multiple sclerosis: An in vivo study using [11C]UCB-J-PET imaging (2024)

P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study (2024)

TSPO-PET-measurable microglial activity remains unaltered in cladribine-treated RRMS patients (2024)

PET-measurable innate immune cell activation reduction in chronic active lesions in PPMS brain after rituximab treatment: a case report (2023)

Longitudinal stability of progression-related microglial activity during teriflunomide treatment in patients with multiple sclerosis (2023)

The alpha2C-adrenoceptor as a neuropsychiatric drug tar-get - PET studies in human subjects (2015)