Kalle Rytkönen profile picture

Kalle
Rytkönen

Docent, Institute of Biomedicine
Senior Research Fellow, Institute of Biomedicine
Senior Research Fellow, InFLAMES Flagship, Institute of Biomedicine / Turku Bioscience Centre

Contact

Tykistökatu 6
20520
Turku

Areas of expertise

Female reproduction
reproductive immunology
uterus
endometrium
endometriosis
preeclampsia
hypoxia
gene regulation
functional genomics
single-cell transcriptomics

Biography

2011, PhD, University of Turku

2012-2015 Post Doc, Prof. Gunter Wagner lab, Yale Systems Biology Institute, Yale University

2016-2018 Marie Curie Research Fellow, Institute of Biomedicine / Turku Centre for Biotechnology

2019- Research Fellow associated with Prof. Laura Elo and Prof. Matti Poutanen groups, Turku Bioscience Centre / Institute of Biomedicine

2022- Adjunct professor, Institute of Biomedicine

Teaching

Lectures in courses: Modern biotechnologies and bioinformatics; Systems biology; Bioinformatics in Drug Discovery.

Research

Current research focuses on the gene regulation of the uterine endometrium and endometrium related disorders such as preeclampsia, endometriosis, PCOS and heavy menstrual bleeding. To better understand the uterine biology and the roles of specific uterine cell types I utilize transcriptomics, steroidomics and computational biology tools.  

Publications

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Serum Hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein a but does not serve as an independent marker for preeclampsia (2024)

Biology of Reproduction
Heinosalo, Taija; Saarinen, Niina; Biehl, Alexander; Rytkönen, Kalle T; Villa, Pia M; Juhila, Juuso; Koskimies, Pasi; Laiho, Asta; Hämäläinen, Esa; Kajantie, Eero; Räikkönen, Katri; Elo, Laura L; Laivuori, Hannele; Poutanen, Matti
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice (2022)

International Journal of Molecular Sciences
Heinosalo Taija, Rytkönen Kalle T., Saarinen Niina, Järvensivu Päivi, Damdimopoulou Pauliina, Strauss Leena, Orasniemi Satu, Horshauge Petricia, Gabriel Michael, Koskimies Pasi, Ohlsson Claes, Kronqvist Pauliina, Poutanen Matti
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )