Kari Kopra

Label-free technique for universal and sequence independent detection of oligonucleotides and nuclease activity (2025)

Nucleic Acids Research

Gooran, Negin; Borsa, Baris A; Hernandez, Frank J; Härmä, Harri; Kopra, Kari

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner (2025)

Molecular Oncology

Kapp, Jonas N.; Verdurmen, Wouter P. R.; Schaefer, Jonas V.; Kopra, Kari; Nagy‐Davidescu, Gabriela; Richard, Elodie; Nokin, Marie‐Julie; Ernst, Patrick; Tamaskovic, Rastislav; Schwill, Martin; Degen, Ralph; Scholl, Claudia; Santamaria, David; Plückthun, Andreas

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

ADP-ribosyltransferase-based biocatalysis of non-hydrolyzable NAD+ analogs (2025)

Journal of Biological Chemistry

Sakari, Moona; Bhadane, Rajendra; Kumar, Sujit; Azevedo, Rita; Malakoutikhah, Morteza; Masoumi, Ahmadreza; Littler, Dene R; Härmä, Harri; Kopra, Kari; Pulliainen, Art To

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

A nucleotide-independent, pan-RAS-targeted DARPin elicits anti-tumor activity in a multimodal manner (2025)

Molecular Oncology

Kapp, Jonas N.; Verdurmen, Wouter P. R.; Schaefer, Jonas V.; Kopra, Kari; Nagy-Davidescu, Gabriela; Richard, Elodie; Nokin, Marie-Julie; Ernst, Patrick; Tamaskovic, Rastislav; Schwill, Martin; Degen, Ralph; Scholl, Claudia; Santamaria, David; Plückthun, Andreas

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations (2025)

Scientific Reports

Leini, Renne; Kapp, Jonas; Kopra, Kari; Pantsar, Tatu

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Early insulin fibril detection: Insulin fibril research and TR structural transition detection with FRET-Probe (2025)

Analytica Chimica Acta

Malakoutikhah, Morteza; Kauppi, Laura; Mäntylä, Kalle; Härmä, Harri; Kopra, Kari

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Luminescence-Based Techniques for KRAS Thermal Stability Monitoring (2024)

Methods in Molecular Biology

Kopra Kari

(Vertaisarvioitu artikkeli kokoomateoksessa (A3))

Label-free electronic detection of peptide post-translational modification with functional enzyme-driven assay at the physical limit (2024)

Cell Reports Physical Science

Macchia, Eleonora; Björkström, Kim; Tewari, Amit; Eskonen, Ville; Luukkonen, Axel; Ghafari, Amir Mohammad; Sarcina, Lucia; Caputo, Mariapia; Tong-Ochoa, Natalia; Kopra, Kari; Pettersson, Fredrik; Gounani, Zahra; Torsi, Luisa; Härmä, Harri; Österbacka, Ronald

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Fluorescence-Based Protein Stability Monitoring : A Review (2024)

International Journal of Molecular Sciences

Gooran Negin, Kopra Kari

(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä)

Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96 (2024)

ACS Chemical Biology

Mahran, Randa; Kapp, Jonas N.; Valtonen, Salla; Champagne, Allison; Ning, Jinying; Gillette, William; Stephen, Andrew G.; Hao, Feng; Pluckthun, Andreas; Härmä, Harri; Pantsar, Tatu; Kopra, Kari

(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Kari

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Label-free technique for universal and sequence independent detection of oligonucleotides and nuclease activity (2025)

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner (2025)

ADP-ribosyltransferase-based biocatalysis of non-hydrolyzable NAD+ analogs (2025)

A nucleotide-independent, pan-RAS-targeted DARPin elicits anti-tumor activity in a multimodal manner (2025)

Binding modes of the KRAS(G12C) inhibitors GDC-6036 and LY3537982 revealed by all atom molecular dynamics simulations (2025)

Early insulin fibril detection: Insulin fibril research and TR structural transition detection with FRET-Probe (2025)

Luminescence-Based Techniques for KRAS Thermal Stability Monitoring (2024)

Label-free electronic detection of peptide post-translational modification with functional enzyme-driven assay at the physical limit (2024)

Fluorescence-Based Protein Stability Monitoring : A Review (2024)

Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96 (2024)