Markus Juonala profile picture
Markus
Juonala
Professor, Internal Medicine
Professor
Cardiovascular epidemiology, Young Finns Study, i3c consortium

Contact

+358 29 450 2754
+358 50 478 3572

Areas of expertise

Internal medicine
endocrinology
cardiovascular risk

Biography

Professor Markus Juonala (MD, PhD, University of Turku) is a specialist in internal medicine and endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he has been conducting research on longitudinal studies examining the importance of childhood risk factors on later cardiovascular health. His PhD work was based primarily on the Cardiovascular Risk in Young Finns Study (University of Turku, April 2005). Since 2008, he has had a major involvement in the development of the International Childhood Cardiovascular Cohort (i3C) Consortium that combines the efforts of the main longitudinal studies worldwide. In June 2014, he was appointed as Professor of Internal Medicine at the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute (MCRI). 

His career publications total is 270 (h-index 44) with published highlights including a first-author paper in the New England Journal of Medicine, the first-ranked general medicine journal, one paper in JAMA, the third-ranked general medicine journal and 30 papers (11 as first/last author) published in either the number one, two, or three ranked cardiovascular disease journals (17 in Circulation, five in the Journal of the American College of Cardiology, eight in the European Heart Journal). 

Teaching

Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs

Special interest areas: Acute internal medicine, endocrinology, lipidology

  

Research

Professor Juonala’s principal research focus has been to provide novel information on the effects of childhood risk factors on cardiovascular health in adulthood. Beginning from the summer of 2008 he has led a research group within the Young Finns Study and i3c consortium with special interest on cardiometabolic risk factors. The most important findings of his research have provided information on childhood and early adulthood risk factors for atherosclerosis, suggesting that childhood risk factors, such as dyslipidaemia, elevated blood pressure and smoking, predict early atherosclerosis and its progression independent of adult risk factors levels. Concerning cardiometabolic risk factors, his group has been able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood is predictive of carotid atherosclerosis and its progression in adulthood. However, at the time of obesity epidemic, the most important findings concern the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes in lifestyle associated with weight maintenance or reduction improve cardiovascular health.

 


Publications

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Association of Body Mass Index in Youth With Adult Cardiometabolic Risk (2020)

Journal of the American Heart Association
Wu FT, Juonala M, Sabin MA, Buscot MJ, Pahkala K, Smith KJ, Hutri-Kahonen N, Kahonen M, Laitinen TP, Viikari JSA, Raitakari OT, Magnussen CG
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Cross-sectional metabolic profiles of mental health in population-based cohorts of 11-to 12-year-olds and mid-life adults: The Longitudinal Study of Australian Children (2020)

Australian and New Zealand Journal of Psychiatry
Katherine Lange, Kate Lycett, Susan Ellul, Richard Saffery, Fiona Mensah, John Carlin, Lisa Gold, Ben Edwards, Peter Azzopardi, Michael Sawyer, Markus Juonala, Davis Burgner, Melissa Wake
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Effects of 20-year infancy-onset dietary counselling on cardiometabolic risk factors in the Special Turku Coronary Risk Factor Intervention Project (STRIP): 6-year post-intervention follow-up (2020)

The Lancet Child & Adolescent Health
Katja Pahkala, Tomi T. Laitinen, Harri Niinikoski, Noora Kartiosuo, Suvi P. Rovio, Hanna Lagström, Britt-Marie Loo, Pia Salo, Eero Jokinen, Costan G. Magnussen, Markus Juonala, Olli Simell, Antti Jula, Tapani Rönnemaa, Jorma Viikari, Olli T. Raitakari
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Non-HDL Cholesterol Levels in Childhood and Carotid Intima-Media Thickness in Adulthood (2020)

Pediatrics
Markus Juonala, Feitong Wu, Alan Sinaiko, Jessica G. Woo, Elaine M. Urbina, David Jacobs, Julia Steinberger, Ronald Prineas, Juha Koskinen, Matthew A. Sabin, David P. Burgner, Trudy L. Burns, Lydia Bazzano, Alison Venn, Jorma S.A. Viikari, Nina Hutri-Kähönen, Stephen R. Daniels, Terence Dwyer, Olli T. Raitakari, Costan G. Magnussen
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers (2020)

Nature Medicine
Mars Nina, Koskela Jukka T., Ripatti Pietari, Kiiskinen Tuomo T. J., Havulinna Aki S., Lindbohm Joni V., Ahola-Olli Ari, Kurki Mitja, Karjalainen Juha, Palta Priit, Neale Benjamin M., Daly Mark, Salomaa Veikko, Palotie Aarno, Widén Elisabeth, Ripatti Samuli; FinnGen
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Attainment of Targets of the 20-Year Infancy-Onset Dietary Intervention and Blood Pressure Across Childhood and Young Adulthood The Special Turku Coronary Risk Factor Intervention Project (STRIP) (2020)

Hypertension
Laitinen Tomi T., Nuotio Joel, Niinikoski Harri, Juonala Markus, Rovio Suvi P., Viikari Jorma S.A., Rönnemaa Tapani, Magnussen Costan G., Sabin Matthew, Burgner David, Jokinen Eero, Lagström Hanna, Jula Antti, Simell Olli, Raitakari Olli T., Pahkala Katja
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))