Markus Juonala profile picture
Markus
Juonala
Professor, Internal Medicine
Professor
Cardiovascular epidemiology, Young Finns Study, i3c consortium

Contact

+358 29 450 2754
+358 50 478 3572

Areas of expertise

Internal medicine
endocrinology
cardiovascular risk

Biography

Professor Markus Juonala (MD, PhD, University of Turku) is a specialist in internal medicine and endocrinology at the Turku University Hospital, Turku, Finland. Since 2001, he has been conducting research on longitudinal studies examining the importance of childhood risk factors on later cardiovascular health. His PhD work was based primarily on the Cardiovascular Risk in Young Finns Study (University of Turku, April 2005). Since 2008, he has had a major involvement in the development of the International Childhood Cardiovascular Cohort (i3C) Consortium that combines the efforts of the main longitudinal studies worldwide. In June 2014, he was appointed as Professor of Internal Medicine at the University of Turku. In 2014-2015 and 2018-2019 he has been working as the Dame Elisabeth Murdoch Fellow in Murdoch Childrens Research Institute (MCRI). 

His career publications total is 270 (h-index 44) with published highlights including a first-author paper in the New England Journal of Medicine, the first-ranked general medicine journal, one paper in JAMA, the third-ranked general medicine journal and 30 papers (11 as first/last author) published in either the number one, two, or three ranked cardiovascular disease journals (17 in Circulation, five in the Journal of the American College of Cardiology, eight in the European Heart Journal). 

Teaching

Teaching responsibilities: 1) Internal medicine for medical students, 2) Internal medicine specialisation programme for MDs

Special interest areas: Acute internal medicine, endocrinology, lipidology

  

Research

Professor Juonala’s principal research focus has been to provide novel information on the effects of childhood risk factors on cardiovascular health in adulthood. Beginning from the summer of 2008 he has led a research group within the Young Finns Study and i3c consortium with special interest on cardiometabolic risk factors. The most important findings of his research have provided information on childhood and early adulthood risk factors for atherosclerosis, suggesting that childhood risk factors, such as dyslipidaemia, elevated blood pressure and smoking, predict early atherosclerosis and its progression independent of adult risk factors levels. Concerning cardiometabolic risk factors, his group has been able to show that overweight and metabolic syndrome diagnosed either in childhood or adulthood is predictive of carotid atherosclerosis and its progression in adulthood. However, at the time of obesity epidemic, the most important findings concern the reversibility of cardiovascular risk. His work has demonstrated that although overweight and metabolic syndrome are predictive of early atherosclerosis, favourable changes in lifestyle associated with weight maintenance or reduction improve cardiovascular health.

 


Publications

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Childhood age and associations between childhood metabolic syndrome and adult risk for metabolic syndrome, type 2 diabetes mellitus and carotid intima media thickness: The international childhood cardiovascular cohort consortium (2017)

Journal of the American Heart Association
Juha Koskinen, Costan G. Magnussen, Alan Sinaiko, Jessica Woo, Elaine Urbina, David R. Jacobs, Julia Steinberger, Ronald Prineas, Matthew A. Sabin, Trudy Burns, Gerald Berenson, Lydia Bazzano, Alison Venn, Jorma S.A. Viikari, Nina Hutri‐Kähönen, Olli Raitakari, Terence Dwyer, Markus Juonala
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Fasting Glucose and the Risk of Depressive Symptoms: Instrumental-Variable Regression in the Cardiovascular Risk in Young Finns Study (2017)

International Journal of Behavioral Medicine
Karolina Wesołowska, Marko Elovainio, Taina Hintsa, Markus Jokela, Laura Pulkki-Råback, Niina Pitkänen, Jari Lipsanen, Janne Tukiainen, Leo-Pekka Lyytikäinen, Terho Lehtimäki, Markus Juonala, Olli Raitakari, Liisa Keltikangas-Järvinen
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults (2017)

PLoS Genetics
Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue LT, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, Qi QB, Ngwa JS, Renström F, Quaye L, Eicher JD, Hayes JE, Cornelis M, Kutalik Z, Lim E, Luan J, Huffman JE, Zhang WH, Zhao W, Griffin PJ, Haller T, Ahmad S, Marques-Vidal PM, Bien S, Yengo L, Teumer A, Smith AV, Kumari M, Harder MN, Justesen JM, Kleber ME, Hollensted M, Lohman K, Rivera NV, Whitfield JB, Zhao JH, Stringham HM, Lyytikäinen LP, Huppertz C, Willemsen G, Peyrot WJ, Wu Y, Kristiansson K, Demirkan A, Fornage M, Hassinen M, Bielak LF, Cadby G, Tanaka T, Magl R, Van der Most PJ, Jackson AU, Bragg-Gresham JL, Vitart V, Marten J, Navarro P, Bellis C, Pasko D, Johansson A, Snitker S, Cheng YC, Eriksson J, Lim U, Aadahl M, Adair LS, Amin N, Balkau B, Auvinen J, Beilby J, Bergman RN, Bergmann S, Bertoni AG, Blangero J, Bonnefond A, Bonnycastle LL, Borja JB, Brage S, Busonero F, Buyske S, Campbell H, Chines PS, Collins FS, Corre T, Smith GD, Delgado GE, Dueker N, Dorr M, Ebeling T, Eiriksdottir G, Esko T, Faul JD, Fu M, Faerch K, Gieger C, Glaser S, Gong J, Gordon-Larsen P, Grallert H, Grammer TB, Grarup N, van Grootheest G, Harald K, Hastie ND, Havulinna AS, Hernandez D, Hindorff L, Hocking LJ, Holmens OL, Holzapfel C, Hottenga JJ, Huang J, Huang T, Hui J, Huth C, Hutri-Kähönen N, James AL, Jansson JO, Jhun MA, Juonala M, Kinnunen L, Koistinen HA, Kolcic I, Komulainen P, Kuusisto J, Kvaløy K, Kähönen M, Lakka TA, Launer LJ, Lehne B, Lindgren CM, Lorentzon M, Luben R, Marre M, Milaneschi Y, Monda KL, Montgomery GW, De Moor MHM, Mulas A, Müller-Nurasyid M, Musk AW, Männikkö R, Männistö S, Narisu N, Nauck M, Nettleton JA, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Paternoster L, Perez J, Perola M, Peters A, Peters U, Peyser PA, Prokopenko I, Puolijoki H, Raitakari OT, Rankinen T, Rasmussen-Torvik LJ, Rawal R, Ridker PM, Rose LM, Rudan I, Sarti C, Sarzynski MA, Savonen K, Scott WR, Sanna S, Shuldiner AR, Sidney S, Silbernagel G, Smith BH, Smith JA, Snieder H, Stančáková A, Sternfeld B, Swift AJ, Tammelin T, Tan ST, Thorand B, Thuillier D, Vandenput L, Vestergaard H, van Vliet-Ostaptchouk JV, Vohl MC, Völker U, Waeber G, Walker M, Wild S, Wong A, Wright AF, Zillikens MC, Zubair N, Haiman CA, Lemarchand L, Gyllensten U, Ohlsson C, Ohlsson C, Hofman A, Rivadeneira F, Uitterlinden AG, Pérusse L, Wilson JF, Hayward C, Polasek O, Cucca F, Hveem K, Hartman CA, Tönjes A, Bandinelli S, Palmer LJ, Kardia SLR, Rauramaa R, Sørensen TIA, Tuomilehto J, Salomaa V, Penninx BWJH, de Geus EJC, Boomsma DI, Lehtimaki T, Mangino M, Laakso M, Bouchard C, Martin NG, Kuh D, Liu YM, Linneberg A, Marz W, Strauch K, Kivimäki M, Harris TB, Gudnason V, Völzke H, Qi L, Järvelin MR, Chambers JC, Kooner JS, Froguel P, Kooperberg C, Vollenweider P, Hallmans G, Hansen T, Pedersen O, Metspalu A, Wareham NJ, Langenberg C, Weir DR, Porteous DJ, Boerwinkle E, Chasman DI, Abecasis GR, Barroso I, McCarthy MI, Frayling TM, O'Connell JR, van Duijn CM, Boehnke M, Heid IM, Mohlke KL, Strachan DP, Fox CS, Liu CT, Hirschhorn JN, Klein RJ, Johnson AD, Borecki IB, Franks PW, North KE, Cupples LA, Loos RJF, Kilpeläinen TO, Klein RJ, Hirschhorn JN, Liu CT, Fox CS, North KE, Franks PW, Borecki IB, Johnson AD, Kilpeläinen TO, Loos RJF, Cupples LA, Mohlke KL, Strachan DP
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))