Matti Poutanen profile picture
Professor, Institute of Biomedicine
InFLAMES Flagship


+358 29 450 2632
+358 50 366 0140
Kiinamyllynkatu 10

Areas of expertise

gentically modified mice
sex steroids
hormonal cancer



1987, M.Sc., Department of Biochemistry, University of Oulu, Finland

1993, Ph.D., Department of Clinical Chemistry, University of Oulu, Finland         

1997, Title of Docent (Adjunct professor); Biochemical Endocrinology, University of Oulu, Finland   


Professor, Department of Physiology, University of Turku, and Director of Turku Center for Disease Modeling, University of Turku, Finland

Senior Scientist lecturer, Institute of Medicine, The Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden

Academy of Finland, The Finnish Cancer Organisations, Sigrid Juselius Foundation, Novo Foundation, Vetenskaps Rådet, Business Finland and Industry

SUPERVISION OF STUDENTS: 30 PhD students supervised, 6 in training.


Research is mainly focused on sex steroid synthesis and action, with total number of citation 6270 (Web of Science, April 2018); number of citations in 2017: ~400; average citations per article: 26.8; h-index: 46; 182 original peer-reviewed publications; 5 publications in high-impact journals (I.F. ≥ 10): J. Clin. Invest. 2x (I.F. 13), Cell Metab.(I.F. 17), Nat. Med. (I.F. 28), Gut (I.F. 14)

 Co-founder, Forendo Pharma ltd ( focusing on hormonal therapies for endometriosis and male hypogonadism. The company has closed its investment rounds with the leading Nordic start-up investors Karolinska Development AB, Novo Seeds and Finnvera. 


Teaching experience in, endocrinology, developmental biology, hormonal cancer, GM mice and animal models and in vivo imaging


Our research group has been internationally in a key position in providing evidence for the concept where the ligand concentration available for steroid hormone receptor binding is markedly regulated by the target tissue metabolism, termed intracrine steroid hormone action. The concept has proven to be essential for the growth and progression of both prostate and breast cancer. We, furthermore, have shown this concept to be valid also in premenopausal women, eg. in the endometriosis, and other medically relevant implications are expected to rise in the near future.


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Differences in Gut Microbiota Profiles and Microbiota Steroid Hormone Biosynthesis in Men with and Without Prostate Cancer (2024)

European Urology Open Science
Kalinen Sofia, Kallonen Teemu, Gunell Marianne, Ettala Otto, Jambor Ivan, Knaapila Juha, Syvänen Kari T., Taimen Pekka, Poutanen Matti, Aronen Hannu J., Ollila Helena, Pietilä Sami, Elo Laura L., Lamminen Tarja, Hakanen Antti J., Munukka Eveliina, Boström Peter J.; the Multi-IMPROD Study Group
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Dissecting the KNDy hypothesis: KNDy neuron-derived kisspeptins are dispensable for puberty but essential for preserved female fertility and gonadotropin pulsatility (2023)

Velasco I, Franssen D, Daza-Dueñas S, Skrapits K, Takács S, Torres E, Rodríguez-Vazquez E, Ruiz-Cruz M, León S, Kukoricza K, Zhang FP, Ruohonen S, Luque-Cordoba D, Priego-Capote F, Gaytan F, Ruiz-Pino F, Hrabovszky E, Poutanen M, Vázquez MJ, Tena-Sempere M
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Deep Learning-Based Image Analysis of Liver Steatosis in Mouse Models (2023)

American Journal of Pathology
Mairinoja Laura, Heikelä Hanna, Blom Sami, Kumar Darshan, Knuuttila Anna, Boyd Sonja, Sjöblom Nelli, Birkman Eva-Maria, Rinne Petteri, Ruusuvuori Pekka, Strauss Leena, Poutanen Matti
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))