Olli Tenovuo profile picture
Olli
Tenovuo
Professor, Clinical Neurosciences
MD, PhD, Prof. of Neurotraumatology
Pathophysiology, diagnostics, treatment, and prognosis of traumatic brain injury

Contact

Areas of expertise

traumatic brain injury
rehabilitation
biomarkers
imaging

Biography

I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 40 researchers, 21 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.

Teaching

Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.

Research

The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.

Publications

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Acute Kidney Injury in Traumatic Brain Injury Patients: Results From the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study (2021)

Critical Care Medicine
Robba Chiara, Banzato Erika, Rebora Paola, Iaquaniello Carolina, Huang Chao-Yuan, Wiegers Eveline JA, Meyfroidt Geert, Citerio Giuseppe; for The Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) ICU Participants and Investigators
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Brain Tissue Oxygen and Cerebrovascular Reactivity in Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Exploratory Analysis of Insult Burden (2020)

Journal of Neurotrauma
Zeiler FA, Beqiri E, Cabeleira M, Hutchinson PJ, Stocchetti N, Menon DK, Czosnyka M, Smielewski P, Ercole A; the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) High-Resolution ICU (HR ICU) Sub-Study Participants and Investigators
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Systemic markers of injury and injury response are not associated with impaired cerebrovascular reactivity in adult TBI: A CENTER-TBI study (2020)

Journal of Neurotrauma
Zeiler FA, Mathieu F, Monteiro MAB, Glocker B, Ercole A, Cabeleira M, Stocchetti N, Smielewski P, Czosnyka M, Newcombe V, Menon D; the Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) High-Resolution ICU (HR ICU) Sub-Study Participants and Investigators
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)