Oxana Denisova profile picture

Oxana
Denisova

Turku Bioscience Centre
PhD

Areas of expertise

Cancer cell signaling
kinases
protein phosphatase 2A
anticancer and antiviral agents, virus-host interaction

Biography

Education and degrees completed

26th August 2014 Ph.D. in Medicine (Molecular Virology), Faculty of Medicine, University of Helsinki, Finland. Topic: "Influenza virus-host interactions and their modulation by small molecules".

29th June 2007 M.Sc. in Biology (Molecular Biology) (Hons.), Lobachevsky State University of Nizhny Novgorod, Russia. Topic: "Development of genomic approach for high-throughput analysis of CCWGG methylation".

09.2005 – 05.2007 training at the Molecular Biology Education Centre, Institute of Protein Research, Pushchino, Russia, included in MSc degree. Topic: "Cloning and purification of site-specific endonuclease EcoRIIC".

Current position

01.2015 – present Postdoctoral researcher at Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.

Previous work experience

06.2011 – 05.2014 PhD researcher, Institute for Molecular Medicine Finland, Helsinki, Finland.

10.2008 – 10.2011 Researcher, Institute of Theoretical and Experimental Biophysics, Pushchino, Russia.

09.2007 – 10.2008 Researcher, Institute of Protein Research, Pushchino, Russia.

Career breaks

05.2016 – 08.2017 Maternity leave.

Publications

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PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells (2023)

Molecular Oncology
Denisova Oxana V., Merisaari Joni, Huhtaniemi Riikka, Qiao Xi, Yetukuri Laxman, Jumppanen Mikael, Kaur Amanpreet, Pääkkönen Mirva, von Schantz-Fant Carina, Ohlmeyer Michael, Wennerberg Krister, Kauko Otto, Koch Raphael, Aittokallio Tero, Taipale Mikko, Westermarck Jukka
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide (2019)

International Journal of Cancer
Tor‐Christian Johannessen, Md Mahdi Hasan‐Olive, Huaiyang Zhu, Oxana Denisova, Amra Grudic, Md Abdul Latif, Halala Saed, Jobin K. Varughese, Gro Vatne Røsland, Ning Yang, Terje Sundstrøm, Anne Nordal, Karl Johan Tronstad, Jian Wang, Morten Lund‐Johansen, Anne Simonsen, Bassam Janji, Jukka Westermarck, Rolf Bjerkvig, Lars Prestegarden
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

PP2A inhibitor PME-1 drives kinase inhibitor resistance in glioma cells (2016)

Cancer Research
Amanpreet Kaur, Oxana V. Denisova, Xi Qiao, Mikael Jumppanen, Emilia Peuhu, Shafiq U. Ahmed, Olayinka Raheem, Hannu Haapasalo, John Eriksson, Anthony J. Chalmers, Pirjo Laakkonen, Jukka Westermarck
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))