Pekka Taimen profile picture
Pekka
Taimen
Professor, Institute of Biomedicine
InFLAMES Flagship
MD, PhD

Contact

+358 29 450 4524
+358 50 431 1353
Kiinamyllynkatu 10
20520
Turku

Areas of expertise

pathology
histology
cell biology
prostate cancer, bladder cancer, cardiomyopathy, nuclear lamin

Biography

Pekka Taimen received his MD degree from the University of Turku in 2001 and defended his thesis at the Department of Pathology, University of Turku in 2004. In 2008-2009 PT worked as a postdoctoral fellow in the laboratory of Prof. Robert D. Goldman, Northwestern University Medical School, Chicago. Postdoctoral studies focusing on nuclear intermediate filament proteins called lamins were further continued as a junior group leader after returning back to Turku in early 2010. In 2011 PT received a specialist degree in Pathology and since then he has worked as a part-time specialist at the Pathology Division, Turku University Hospital with special focus on uropathology. From 2012 PT has worked as a Clinical lecturer in Pathology and between 2015-2019 as a part-time Academy of Finland Clinical Researcher. PT was appointed as a tenure track Assistant Professor of Molecular Pathology in January 2019 and an Associate Professor in August 2020. In January 2022, PT was appointed as a Professor of Molecular Pathology and he currently serves as the head of the pathology unit at the Faculty of Medicine, University of Turku.

Teaching

Pekka Taimen has more than 10 years of experience in teaching medical students at the Institute of Biomedicine, University of Turku. He has served first as a university teacher and from 2012 as a clinical lecturer. In 2015 PT received the Lecturer of the Year award in the Faculty of Medicine.

Research

Professor Pekka Taimen has 20 years of experience in cell and molecular biology as well as in translational research. The main focus of his research group is on human diseases caused by lamin mutations, such as cardiomyopathies and premature aging syndrome. More recently, PT has also actively worked on prostate and bladder cancer related projects including novel biomarkers, biobanking, patient derived cell lines and improved imaging techniques utilizing digital pathology and machine learning approaches.

Publications

Sort by:

Predicting the Need for Biopsy to Detect Clinically Significant Prostate Cancer in Patients with a Magnetic Resonance Imaging–detected Prostate Imaging Reporting and Data System/Likert ≥3 Lesion: Development and Multinational External Validation of the Imperial Rapid Access to Prostate Imaging and Diagnosis Risk Score (2022)

European Urology
Peters M., Eldred-Evans D., Kurver P., Falagario U.G., Connor M.J., Shah T.T., Verhoeff J.J.C., Taimen P., Aronen H.J., Knaapila J., Montoya Perez I., Ettala O., Stabile A., Gandaglia G., Fossati N., Martini A., Cucchiara V., Briganti A., Lantz A., Picker W., Haug E.S., Nordström T., Tanaka M.B., Reddy D., Bass E., van Rossum P.S.N., Wong K., Tam H., Winkler M., Gordon S., Qazi H., Boström P.J., Jambor I., Ahmed H.U.
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations (2022)

Nature Communications
Le Dour Caroline, Chatzifrangkeskou Maria, Macquart Coline, Magiera Maria M., Peccate Cécile, Jouve Charlène, Virtanen Laura, Heliö Tiina, Aalto-Setälä Katriina, Crasto Silvia, Cadot Bruno, Cardoso Déborah, Mougenot Nathalie, Adesse Daniel, Di Pasquale Elisa, Hulot Jean Sébastien, Taimen Pekka, Janke Carsten, Muchir Antoine
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Negative Predictive Value of Biparametric Prostate Magnetic Resonance Imaging in Excluding Significant Prostate Cancer: A Pooled Data Analysis Based on Clinical Data from Four Prospective, Registered Studies (2021)

European Urology Focus
Juha Knaapila, Ivan Jambor, Otto Ettala, Pekka Taimen, Janne Verho, Ileana Montoya Perez, Aida Kiviniemi, Tapio Pahikkala, Harri Merisaari, Tarja Lamminen, Jani Saunavaara, Hannu J.Aronen, Kari T.Syvänen, Peter J.Boström
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

How to read biparametric MRI in men with a clinical suspicious of prostate cancer: Pictorial review for beginners with public access to imaging, clinical and histopathological database (2021)

Acta Radiologica Open
Jambor Ivan, Martini Albero, Falagario Ugo G, Ettala Otto, Taimen Pekka, Knaapila Juha, Syvänen Kari T, Steiner Aida, Verho Janne, Perez Ileana M, Merisaari Harri, Vainio Paula, Lamminen Tarja, Saunavaara Jani, Carrieri Giuseppe, Boström Peter J, Aronen Hannu J
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))

Prospective comparison of 18F-PSMA-1007 PET/CT, whole-body MRI and CT in primary nodal staging of unfavourable intermediate- and high-risk prostate cancer (2021)

European Journal of Nuclear Medicine and Molecular Imaging
Malaspina Simona, Anttinen Mikael, Taimen Pekka, Jambor Ivan, Sandell Minna, Rinta-Kiikka Irina, Kajander Sami, Schildt Jukka, Saukko Ekaterina, Noponen Tommi, Saunavaara Jani, Dean Peter B, Sequeiros Roberto Blanco, Aronen Hannu J, Kemppainen Jukka, Seppänen Marko, Boström Peter J, Ettala Otto
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Computer extracted gland features from H&E predicts prostate cancer recurrence comparably to a genomic companion diagnostic test: a large multi-site study (2021)

npj Precision Oncology
Leo Patrick, Janowczyk Andrew, Elliott Robin, Janaki Nafiseh, Bera Kaustav, Shiradkar Rakesh, Farré Xavier, Fu Pingfu, El-Fahmawi Ayah, Shahait Mohammed, Kim Jessica, Lee David, Yamoah Kosj, Rebbeck Timothy R., Khani Francesca, Robinson Brian D., Eklund Lauri, Jambor Ivan, Merisaari Harri, Ettala Otto, Taimen Pekka, Aronen Hannu J., Boström Peter J., Tewari Ashutosh, Magi-Galluzzi Cristina, Klein Eric, Purysko Andrei, Shih Natalie NC, Feldman Michael, Gupta Sanjay, Lal Priti, Madabhushi Anant
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))