Tapio Lönnberg profile picture

Tapio
Lönnberg

Senior Research Fellow, Turku Bioscience Centre
InFLAMES Flagship
Docent, Biotechnology
PhD
Single-cell immunogenomics research group at Turku Bioscience Centre; InFLAMES Flagship

Contact

Tykistökatu 6
20520
Turku

Links

Lab website
ORCID

Areas of expertise

Single-cell genomics
immunology

Biography

  • Phd 2012, University of Turku, supervised by Prof. Riitta Lahesmaa and Prof. Matej Orešič
  • Postdoc 2023-2016, Teichmann lab, EMBL-EBI and Wellcome Trust Sanger Institute, UK
  • Academy of Finland postdoc 2017-2020, Turku Bioscience Centre, University of Turku
  • 2021- Group Leader at InFLAMES Flagship
  • Secretary of the Finnish Society for Immunology



Teaching

  • Modern biotechnologies and bioinformatics
  • Medical biotechnology
  • Advanced Immunology


Research

Our research aims at gaining deeper understanding of cell fate decisions in the immune system. We leverage single-cell and spatial omics to explore phenotypic heterogeneity beyond the immune cell subsets defined by the expression of cell surface markers. Our current research encompasses arthritic, autoimmune and cardiovascular diseases, aiming to identify core gene modules that are associated with disease state and can be exploited for more efficient diagnosis, patient stratification, and therapies.

Publications

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Single-cell to pre-clinical evaluation of Trem2, Folr2, and Slc7a7 as macrophage-associated biomarkers for atherosclerosis (2025)

Cardiovascular Research
Örd, Tiit; Palani, Senthil; Giroud Gerbetant, Judith; Bodoy, Susanna; Lönnberg, Tapio; Niskanen, Henri; Ravindran, Aarthi; Holappa, Lari; Chemaly, Melody; Taipale, Mari; Õunap, Kadri; Haikonen, Retu; Talukdar, Husain; Sukhavasi, Katyayani; Liljenbäck, Heidi; Virta, Jenni; Ruotsalainen, Anna-Kaisa; Pierrot-Blanchet, Clara; Miner, Maxwell W. G.; Moisio, Olli; Rajala, Noora; Li, Xiang-Guo; Low, Philip S.; Saraste, Antti; Heinäniemi, Merja; Ylä-Herttuala, Seppo; Björkegren, Johan L. M.; Hedin, Ulf; Matic, Ljubica; Yvan-Charvet, Laurent; Palacin, Manuel; Roivainen, Anne; Kaikkonen, Minna U.
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

MicroRNA gene dynamics in immune cell subpopulations during aging and atherosclerosis disease development at single-cell resolution (2025)

de Sande, Ana Hernández; Turunen, Tanja; Bouvy-Liivrand, Maria; Örd, Tiit; Palani, Senthil; Lahnalampi, Mari; Tundidor-Centeno, Celia; Liljenbäck, Heidi; Virta, Jenni; Niskanen, Henri; Jayasingha, Buddika; Smålander, Olli-Pekka; Sinkkonen, Lasse; Mikkola, Lea; Sauter, Thomas; Roivainen, Anne; Lönnberg, Tapio; Kaikkonen, Minna U.; Heinäniemi, Merja
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Breast cancer remodels lymphatics in sentinel lymph nodes (2025)

Eichin, Dominik; Lehotina, Diana; Kauko, Anni; Uenaka, Maki; Leppänen, Meri; Elima, Kati; Piipponen, Minna; Lönnberg, Tapio; Boström, Pia; Koskivuo, Ilkka; Aittokallio, Tero; Hollmén, Maija; Takeda, Akira; Jalkanen, Sirpa
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
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