Teemu Niiranen profile picture
Teemu
Niiranen
Professor, Internal Medicine
MD, PhD

Contact

Areas of expertise

Cardiovascular epidemiology
cohort studies
blood pressure
hypertension
blood pressure measurement

Biography

Teemu Niiranen, MD, PhD, is a physician-scientist and a clinical hypertension specialist with a track record of productivity in hypertension research, successful mentoring, international research grant procurement, and inter-institutional international collaborations. His research on hypertension in large population cohorts has led to >200 publications that are cited by the European, American, British, and Japanese clinical hypertension guidelines. These publications include first- or last-author articles in BMJ, Circulation, European Heart Journal, Nature Communications and JAMA Cardiology.

After finishing his PhD and clinical training, Dr. Niiranen received in-depth training in cardiovascular disease epidemiology and omics during a post-doctoral period at the Framingham Heart Study, the oldest and most prestigious cardiovascular cohort study in the world. After his post-doctoral period, he was selected as one of the new Group Leaders of the University of Turku Collegium of Science and Medicine and in 2020, the professor of internal medicine at the university. He is also employed as a Medical Specialist by the National Institute for Health and Welfare and chairs the work of the Cardiometabolic Clinical Expert Group of the FinnGen study, a project that has genotyped up to 500 000 unique Finnish blood samples and merged this genetic data with nationwide healthcare registers.

Dr. Niiranen has received young investigator awards from the American and Finnish Societies of Hypertension, and the American Heart Association. He is the chair of the Finnish Hypertension Society and is currently mentoring, or has mentored 12 PhD students. He is an editorial board member of Hypertension, the leading journal in hypertension research.

Teaching

Semester leadership: Fall Semester, Clinical research path for fourth year medical students.

Course leadership: PGS1728: Getting Started with Medical Research (Year 4); PGS1741: Clinical Research Literature Exam (Year 4)

Course teaching: MEDI0117: General Propedeutics (Year 4)

Pedagogic training: Medical Pedagogy course (10 credits)

Research

In addition to general cardiovascular epidemiology, Dr. Niiranen's research has focused on the epidemiology of hypertension in large scale population cohorts. His studies particularly focused on home monitoring of blood pressure and more recently he has moved into examining the relation between hypertension and omics (genome, metagenome and metabolome).

Publications

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Derivation of an Outcome-Driven Threshold for Aortic Pulse Wave Velocity: An Individual-Participant Meta-Analysis (2023)

Hypertension
An De-Wei, Hansen Tine W., Aparicio Lucas S., Chori Babangida, Huang Qi-Fang, Wei Fang-Fei, Cheng Yi-Bang, Yu Yu-Ling, Sheng Chang-Sheng, Gilis-Malinowska Natasza, Boggia José, Wojciechowska Wiktoria, Niiranen Teemu J., Tikhonoff Valérie, Casiglia Edoardo, Narkiewicz Krzysztof, Stolarz-Skrzypek Katarzyna, Kawecka-Jaszcz Kalina, Jula Antti M., Yang Wen-Yi, Woodiwiss Angela J., Filipovský Jan, Wang Ji-Guang, Rajzer Marek W., Verhamme Peter, Nawrot Tim S., Staessen Jan A., Li Yan; International Database of Central Arterial Properties for Risk Stratification Investigators
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Requirements for design and function of blood pressure measuring devices used for the management of hypertension: Consensus Statement by the European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability and STRIDE BP (2023)

Journal of Hypertension
Stergiou George S., Parati Gianfranco, Kollias Anastasios, Schutte Aletta E., Asayama Kei, Asmar Roland, Bilo Grzegorz, de la Sierra Alejandro, Dolan Eamon, Filipovsky Jan, Head Geoffrey, Kario Kazuomi, Kyriakoulis Konstantinos G., Mancia Giuseppe, Manios Efstathios, Menti Ariadni, McManus Richard J., Mihailidou Anastasia S., Muntner Paul, Niiranen Teemu, Ohkubo Takayoshi, Omboni Stefano, Protogerou Athanasios, Saladini Francesca, Sharman James, Shennan Andrew, Shimbo Daichi, Topouchian Jirar, Wang Jiguang, O'Brien Eoin, Palatini Paolo
(Kirjoitus tai data-artikkeli tieteellisessä aikakauslehdessä (B1))

Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases (2023)

Nature Medicine
Kiiskinen T, Helkkula P, Krebs K, Karjalainen J, Saarentaus E, Mars N, Lehisto A, Zhou W, Cordioli M, Jukarainen S, Rämö JT, Mehtonen J, Veerapen K, Räsänen M, Ruotsalainen S, Maasha M; FinnGen, Niiranen T, Tuomi T, Salomaa V, Kurki M, Pirinen M, Palotie A, Daly M, Ganna A, Havulinna AS, Milani L, Ripatti S
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Sex Differences in Myocardial and Vascular Aging (2022)

Circulation Research
Ji Hongwei W, Kwan Alan C, Chen Melanie T, Ouyang David, Ebinger Joseph E, Bell Susan P, Niiranen Teemu J, Bello Natalie A, Cheng Susan
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))

A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts (2022)

BMJ open diabetes research and care
Tuomisto Karolina, Palmu Joonatan, Long Tao, Watrous Jeramie D, Mercader Kysha, Lagerborg Kim A, Andres Allen, Salmi Marko, Jalkanen Sirpa, Vasan Ramachandran S, Inouye Michael, Havulinna Aki S, Tuomilehto Jaakko, Jousilahti Pekka, Niiranen Teemu J, Cheng Susan, Jain Mohit, Salomaa Veikko
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Substantial Fat Loss in Physique Competitors Is Characterized by Increased Levels of Bile Acids, Very-Long Chain Fatty Acids, and Oxylipins (2022)

Metabolites
Sarin Heikki V, Hulmi Juha J, Qin Youwen, Inouye Michael, Ritchie Scott C, Cheng Susan, Watrous Jeramie D, Nguyen Thien-Tu C, Lee Joseph H, Jin Zhezen, Terwilliger Joseph D, Niiranen Teemu, Havulinna Aki, Salomaa Veikko, Pietiläinen Kirsi H, Isola Ville, Ahtiainen Juha P, Häkkinen Keijo, Jain Mohit, Perola Markus
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))