Xiang-Guo Li profile picture
Xiang-Guo
Li
Assistant Professor, Turku PET Centre
Assistant Professor
Radiochemistry, Radiopharmaceuticals, InFLAMES Flagship

Contact

Kiinamyllynkatu 10
20520
Turku

Areas of expertise

Radiochemistry
Radiopharmaceuticals
PET imaging
New drug development

Biography

I am a radiochemist and medicinal chemist working at Turku PET Centre, University of Turku, Finland. I received my PhD degree from the Institute of Biomedicine, Faculty of Medicine, University of Turku, in 2008. Then I was at a Post-doctoral position funded by the Academy of Finland during 2010-2012. I received my Docentship in 2012 from University of Turku. Since 2013, I have been working at Turku PET Centre. At present, I work as an Assistant Professor in Radiochemistry, and Principal Investigator in the InFLAMES Research Flagship.

Teaching

I teach in the courses of Radiopharmaceutical Chemistry, Radiolabeling techniques, Measuring techniques in radiochemistry, PET Basics, and supervise BSc, MSc and PhD students.

Research

Basic research in radiochemistry including methodological development for radiosynthesis and radiolabeling techniques. We have been able to radiolabel many types of molecules including small organic compounds, peptides, antibody and antibody fragments, oligonucleotides, oligosaccharides etc.

Development of new radiopharmaceuticals for PET imaging of inflammatory diseases and immunological diseases.

The radiolabeled molecules are for imaging diseases or for studying disease machanisms with PET.



Publications

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Comparing Folate Receptor β Targeting Tracers in Experimental Myocarditis Model (2022)

Annual Congress of European Association of Nuclear Medicine and Molecular Imaging, European Journal of Nuclear Medicine and Molecular Imaging
Atencio Herre E, Li X, Liljenbäck H, Andriana P, Jahandideh A, Iqbal I, Dillemuth P, Kärnä S, Virta J, Mansour H, Cleveland NA, Low PS, Knuuti J, Saraste A, Roivainen A
(Vertaisarvioimaton konferenssijulkaisu (B3))

Preclinical Evaluation of a Humanized Antibody Against Common Lymphatic Endothelial and Vascular Endothelial Receptor-1, 89Zr-Desferrioxamine-Bexmarilimab, in a Rabbit Model of Renal Fibrosis (2022)

Journal of Nuclear Medicine
Moisio Olli, Virta Jenni, Yatkin Emrah, Liljenbäck Heidi, Palani Senthil, Viitanen Riikka, Miner Maxwell WG, Oikonen Vesa, Tolvanen Tuula, Vugts Danielle J, Taimen Pekka, Li Xiang-Guo, Hollmén Maija, Jalkanen Sirpa, Roivainen Anne
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Highlight selection of radiochemistry and radiopharmacy developments by editorial board (2021)

EJNMMI Radiopharmacy and Chemistry
Aime Silvio, Al-Qahtani Mohammed, Behe Martin, Bormans Guy, Carlucci Giuseppe, DaSilva Jean N., Decristoforo Clemens, Duatti Adriano, Elsinga Philip H., Kopka Klaus, Li Xiang-Guo, Liu Zhibo, Mach Robert H., Middel Oskar, Passchier Jan, Patt Marianne, Penuelas Ivan, Rey Ana, Scott Peter J. H., Todde Sergio, Toyohara Jun, Vugts Danielle, Zhi Yang
(Kirjoitus tai data-artikkeli tieteellisessä aikakauslehdessä (B1))