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Areas of expertise
Biography
University lecturer (2018-, University of Turku, Turku, Finland)
Principal investigator (2013-, University of Turku, Turku, Finland)
Adjunct professor (2012-, University of
Helsinki, Helsinki, Finland)
Post doc (2006-2013, University of Turku, Turku, Finland and Biozentrum, Basel, Switzerland)
PhD (2006, University of Turku, Turku, Finland)
Doctoral student (2001-2006, University of Turku, Turku, Finland)
MSc (2001, University of Oulu, Oulu, Finland)
Teaching
bacteriology; cell biology; cell
signaling; protein chemistry
Research
Turku Cellular Microbiology Laboratory (TCML) studies molecular mechanisms of the host cell-bacterial pathogen interaction. We aim to understand how host cell signaling is regulated in bacterial infection to orchestrate pathogen clearance, and how pathogen utilizes secreted proteins to counterattack the host anti-bacterial response. The main focus is on post-translation modification called ADP-ribosylation, catalyzed both by host cell enzymes and bacterial proteins inside the host cell. Our ultimate goal is to gain molecular knowledge allowing development of new and targeted therapeutics for emerging antibiotic-resistant bacteria.
Funding sources:
Academy of Finland, Sigrid Jusélius Foundation, The Finnish Society of Sciences and Letters, Jenny and Antti Wihuri Foundation, Emil Aaltonen Foundation, Turku University Foundation, University of Turku, Turku Doctoral Programme of Molecular Medicine (TuDMM), Erasmus+