Harri Niinikoski profile picture
Harri
Niinikoski
Professor, Institute of Biomedicine
Professor, Nutrition in Medicine (Institute of Biomedicine)

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Areas of expertise

Childhood endocrinology and nutrition
inherited metabolic diseases
neonatal screening
prevention of cardiovascular risk factors.

Biography

Professor Harri Niinikoski graduated from the Medical School at the University of Turku in 1991, where he also specialized in Pediatrics in 2000 and received subspecialty in Pediatric Endocrinology in 2006. He defended his thesis on prevention of cardiovascular risk factors in childhood in 1997 (The STRIP study). He did his post-doc training at the Childhood Nutrition Research Center at the Baylor School of Medicine, Houston, Texas, in 2001-2003. Subsequently, he worked as a Senior Clinical Researcher and Clinical Lecturer at the Department of Pediatrics, University of Turku, and in 2011-2015 as the Head of the Division of Pediatric Care in Turku University Hospital. From 2015, he has been Professor of Nutrition in Medicine


Teaching

In 2006-2010, Harri Niinikoski worked as a full-time teacher of pediatrics at the Department of Pediatrics, University of Turku.


Research

Professor Harri Niinikoski’s research interest focus on primary prevention of cardiovascular disease, and childhood nutrition, endocrinology and metabolism. Moreover, he has been closely involved in launching the neonatal metabolic screening program which started in Finland in 2015.

Main research projects are 1) The STRIP study (The Special Turku coronary risk factor Intervention Project) which started in 1990 and involved 1062 infants which were randomized into nutrition an intervention or a control group. He is deputy P.I. in STRIP; 2) DIARA2 study which involves 317 children (217 in Turku, 100 in Oulu) whose mothers were treated with either metformin or insulin due to gestational diabetes. The children are now thoroughly investigated at 9 years of age; 3) LPI study. Lysinuric protein intolerance (LPI) is a rare metabolic disease which belongs to the Finnish disease heritage. There are approx. 50 Finnish patients who are annually studied at the Turku University Hospital pediatric metabolic outpatient clinic; 4) Congenital hypothyroidism study. CH has been screened in Finland since 1980, affects 1:2000 newborns and is treated with thyroxine. The outcome of the treatment of CH is investigated in national CH study which is launched in 2018.


Publications

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Lysinuric Protein Intolerance (2018)

GeneReviews
Virginia Nunes, Harri Niinikoski
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))

Maternal and fetal genetic contribution to gestational weight gain (2018)

International Journal of Obesity
Warrington NM, Richmond R, Fenstra B, Myhre R, Gaillard R, Paternoster L, Wang CA, Beaumont RN, Das S, Murcia M, Barton SJ, Espinosa A, Thiering E, Atalay M, Pitkanen N, Ntalla I, Jonsson AE, Freathy R, Karhunen V, Tiesler CMT, Allard C, Crawford A, Ring SM, Melbye M, Magnus P, Rivadeneira F, Skotte L, Hansen T, Marsh J, Guxens M, Holloway JW, Grallert H, Jaddoe VWV, Lowe WL, Roumeliotaki T, Hattersley AT, Lindi V, Pahkala K, Panoutsopoulou K, Standl M, Flexeder C, Bouchard L, Nohr E, Marina L, Kogevinas M, Niinikoski H, Dedoussis G, Heinrich J, Reynolds RM, Lakka T, Zeggini E, Raitakari OT, Chatzi L, Inskip HM, Bustamante M, Hivert MF, Jarvelin MR, Sorensen TIA, Pennell C, Felix JF, Jacobsson B, Geller F, Evans DM, Lawlor DA
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Ideal cardiovascular health in childhood-Longitudinal associations with cardiac structure and function: The Special Turku Coronary Risk Factor Intervention Project (STRIP) and the Cardiovascular Risk in Young Finns Study (YFS) (2017)

International Journal of Cardiology
Laitinen TT, Ruohonen S, Juonala M, Magnussen CG, Mikkila V, Mikola H, Hutri-Kahonen N, Laitinen T, Tossavainen P, Jokinen E, Niinikoski H, Jula A, Viikari JSA, Ronnemaa T, Raitakari OT, Pahkala K
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Genome-wide associations for birth weight and correlations with adult disease (2016)

Nature
Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikainen LP, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Hottenga JJ, Vilor-Tejedor N, Joshi PK, Boh ETH, Ntalla I, Pitkanen N, Mahajan A, van Leeuwen EM, Joro R, Lagou V, Nodzenski M, Diver LA, Zondervan KT, Bustamante M, Marques-Vidal P, Mercader JM, Bennett AJ, Rahmioglu N, Nyholt DR, Ma RCW, Tam CHT, Tam WH, Ganesh SK, van Rooij FJA, Jones SE, Loh PR, Ruth KS, Tuke MA, Tyrrell J, Wood AR, Yaghootkar H, Scholtens DM, Paternoster L, Prokopenko I, Kovacs P, Atalay M, Willems SM, Panoutsopoulou K, Wang X, Carstensen L, Geller F, Schraut KE, Murcia M, van Beijsterveldt CEM, Willemsen G, Appel EVR, Fonvig CE, Trier C, Tiesler CMT, Standl M, Kutalik Z, Bonas-Guarch S, Hougaard DM, Sanchez F, Torrents D, Waage J, Hollegaard MV, de Haan HG, Rosendaal FR, Medina-Gomez C, Ring SM, Hemani G, McMahon G, Robertson NR, Groves CJ, Langenberg C, Luan J, Scott RA, Zhao JH, Mentch FD, MacKenzie SM, Reynolds RM, Lowe WL, Tonjes A, Stumvoll M, Lindi V, Lakka TA, van Duijn CM, Kiess W, Korner A, Sorensen TIA, Niinikoski H, Pahkala K, Raitakari OT, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Melbye M, Campbell H, Wilson JF, Vrijheid M, de Geus EJCN, Boomsma DI, Kadarmideen HN, Holm JC, Hansen T, Sebert S, Hattersley AT, Beilin LJ, Newnham JP, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widen E, Kahonen M, Viikari JS, Lehtimaki T, Vollenweider P, Bonnelykke K, Bisgaard H, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, Pisinger C, Pedersen O, Power C, Hypponen E, Wareham NJ, Hakonarson H, Davies E, Walker BR, Jaddoe VWV, Jarvelin MR, Grant SFA, Vaag AA, Lawlor DA, Frayling TM, Smith GD, Morris AP, Ong KK, Felix JF, Timpson NJ, Perry JRB, Evans DM, McCarthy MI, Freathy RM
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))