Harry Scheinin profile picture
Harry
Scheinin
Adjunct Professor, Institute of Biomedicine
MD

Areas of expertise

Anesthesiology
Clinical Pharmacology
Neuroscience
Positron Emission Tomography

Biography

Harry Scheinin leads the Anesthesia Mechanisms Research Group at the University of Turku, Finland, and has studied the human neurobiology of anesthetic agents for 20 years. He has collaborated with Professor Antti Revonsuo since 2005.

Research

We try to explore the neural correlates of human consciousness using, e.g., modern imaging methods. We aim to separate consciousness from responsiveness, connectedness from disconnection and to compare unconsciousness of physiological sleep with that induced by anesthetic agents. Finding new tools for the distinction of consciousness, connectedness and responsiveness would be groundbreaking and could represent a major leap forward in understanding human consciousness. The results could also help in developing new EEG-based methods to objectively measure consciousness and the depth of general anesthesia. 

Publications

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Foundations of human consciousness: Imaging the twilight zone (2021)

Journal of Neuroscience
Annalotta Scheinin, Oskari Kantonen, Michael Alkire, Jaakko Långsjö, Roosa Kallionpää, Kaike Kaisti, Linda Radek, Jarkko Johansson, Nils Sandman, Mikko Nyman, Mika Scheinin, Tero Vahlberg, Antti Revonsuo, Katja Valli, Harry Scheinin
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Seasonal variation in the brain μ-opioid receptor availability (2021)

Journal of Neuroscience
Lihua Sun, Jing Tang, Heidi Liljenbäck, Aake Honkaniemi, Jenni Virta, Janne Isojärvi, Tomi Karjalainen, Tatu Kantonen, Pirjo Nuutila, Jarmo Hietala, Valtteri Kaasinen, Kari Kalliokoski, Jussi Hirvonen, Harry Scheinin, Semi Helin, Kim Eerola, Eriika Savontaus, Emrah Yatkin, Juha O Rinne, Anne Roivainen, Lauri Nummenmaa
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)

Comparative effects of dexmedetomidine, propofol, sevoflurane, and S-ketamine on regional cerebral glucose metabolism in humans: a positron emission tomography study (2018)

British Journal of Anaesthesia
Laaksonen L., Kallioinen M., Långsjö J., Laitio T., Scheinin A., Scheinin J., Kaisti K., Maksimow A., Kallionpää R.E., Rajala V., Johansson J., Kantonen O., Nyman M., Sirén S., Valli K., Revonsuo A., Solin O., Vahlberg T., Alkire M., Scheinin H.
(A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä)