Ilkka Paatero profile picture
Ilkka
Paatero
Senior Researcher, Turku Bioscience Centre
Ph.D.

Contact

+358 29 450 3789
Tykistökatu 6
20520
Turku

Areas of expertise

cancer
cardiovascular biology
toxicology
microscopy
zebrafish models
model organisms;

Research

My research covers broad range of topics in biomedicine. Current work is dealing mainly with cancer and cardiovascular biology.

My expertise is in application of model organisms, especially zebrafish (Danio rerio), in biomedical research. These models can help to understand and solve biomedical problems efficiently and ethically. Especially, when combined with high-resolution intravital microscopy, these models can give deep insights into developmental and disease processes in vivo. By using fish eggs and embryos, it is also possible to reduce the number of more complex and developed organisms used in research. These models, however, require certain set of skills and knowledge which is not part of the training of most medical and biomedical scientist. To facilite them to utilize the power of zebrafish models to advance their research, I have established a Zebrafish Core under Turku Centre for Biotechnology (University of Turku and Åbo Akademi University).

Publications

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HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis (2024)

Journal of Experimental and Clinical Cancer Research
Schneegans Svenja, Löptien Jana, Mojzisch Angelika, Loreth Desirée, Kretz Oliver, Raschdorf Christoph, Hanssen Annkathrin, Gocke Antonia, Siebels Bente, Gunasekaran Karthikeyan, Ding Yi, Oliveira-Ferrer Leticia, Brylka Laura, Schinke Thorsten, Schlüter Hartmut, Paatero Ilkka, Voß Hannah, Werner Stefan, Pantel Klaus, Wikman Harriet
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

STAT5b is a key effector of NRG-1/ERBB4-mediated myocardial growth (2023)

EMBO Reports
Vaparanta Katri, Jokilammi Anne, Paatero Ilkka, Merilahti Johannes A, Heliste Juho, Hemanthakumar Karthik Amudhala, Kivelä Riikka, Alitalo Kari, Taimen Pekka, Elenius Klaus
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

MYO10-filopodia support basement membranes at pre-invasive tumor boundaries (2022)

Developmental Cell
Peuhu Emilia, Jacquemet Guillaume, Scheele Colinda LGJ, Isomursu Aleksi, Laisne Marie-Catherine, Koskinen Leena M, Paatero Ilkka, Thol Kerstin, Georgiadou Maria, Guzmán Camilo, Koskinen Satu, Laiho Asta, Elo Laura L, Boström Pia, Hartiala Pauliina, van Rheenen Jacco, Ivaska Johanna
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))