Johanna
Lempainen
Docent, Department of Clinical Medicine
Clinical Lecturer, Institute of Biomedicine
Clinical lecturer
Contact
Areas of expertise
pediatrics
pathogenesis of type 1 diabetes
pediatric infections
pediatric immunology
Biography
Docent Johanna Lempainen
graduated from medical school in 2004 (University of Turku) and defended her
PhD theses on pathogenesis of type 1 diabetes in 2009. She received specialist
licence in paediatrics in 2015 and was appointed as a docent of experimental
paediatrics in 2018 (University of Turku). She is currently working as clinical
lecturer at the department of pediatrics at University of Turku and as
specialist at the Unit for Rare Diseases, Turku University Hospital. She
participates in neonatal screening for severe immunodeficiencies and in
laboratory diagnostics of immunodeficiencies. Training for subspecialty in
pediatric infections and immunodeficiencies is ongoing.
Teaching
Docent Lempainen works
as clinical lecturer in pediatrics (part-time) since January 2017.
Research
Docent Lempainen’s
thesis in 2009 focused on the pathogenesis of type 1 diabetes. Since then her
research work has further focused on the heterogeneity of type 1 diabetes
pathogenesis. In 2011 she worked as visiting researcher in the
BabyDiab-diabetes study group in Munich,
Germany. Her current research interests comprise the etiology of beta-cell
autoimmunity in respect of immunological, genetic and epigenetic factors and
disturbances in early microbial contacts and are a part of the prospective
Diabetes Prediction and Prevention (DIPP) study. In addition, she participates
in research projects aiming at early detection of bacterial and viral
infections in infants and children in order to avoid unnecessary antibiotic
exposure. Since January 2020 docent Lempainen is the principal investigator of the Immunogenetics laboratory and PI and member of steering committee in the DIPP study at the University of Turku.
Publications
Long-term neutralization capacity of vaccine and breakthrough infection induced SARS-CoV-2 specific antibodies against omicron subvariants BA.2, XBB.1.5, and JN.1 (2025)
Vaccine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Autoantibody Response Toward Chromatin in Patients With Juvenile Idiopathic Arthritis (2025)
Arthritis and Rheumatology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
22q11.2-deleetio-oireyhtymän hoito ja seuranta (2025)
Duodecim
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä)
Islet autoimmunity and progression to type 1 diabetes in the Finnish DIPP study: comparison between genetically susceptible children with and without an affected first-degree relative (2025)
Diabetologia
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Diabetes, Celiac, and Thyroid‐Related Autoantibodies in HLA Genotyped Ethiopian Children and Adolescents With Type 1 Diabetes: A Cross‐Sectional Study (2025)
Pediatric Diabetes
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
The Frequency but not the Phenotype of Circulating Peripheral T Helper Cells is Increased at Later Stages of Progression to Type 1 Diabetes (2025)
European Journal of Immunology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Neutralizing antibodies after the third COVID-19 vaccination in healthcare workers with or without breakthrough infection (2024)
Communications medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Long-term COVID-19 vaccine- and Omicron infection-induced humoral and cell-mediated immunity (2024)
Frontiers in Immunology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Increased Frequency of the HLA-DRB1*04:04-DQA1*03-DQB1*03:02 Haplotype Among HLA-DQB1*06:02-Positive Children With Type 1 Diabetes (2024)
Diabetes
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Household Transmission and Clinical Features of Respiratory Tract Infections That Were SARS-CoV-2 Positive and Negative (2024)
Journal of Infectious Diseases
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )