Johanna Lempainen profile picture
Johanna
Lempainen
Clinical Lecturer, Paediatrics and Adolescent Medicine
Docent, Department of Clinical Medicine
Clinical Lecturer, Institute of Biomedicine
Clinical lecturer

Areas of expertise

pediatrics
pathogenesis of type 1 diabetes
pediatric infections
pediatric immunology

Biography

Docent Johanna Lempainen graduated from medical school in 2004 (University of Turku) and defended her PhD theses on pathogenesis of type 1 diabetes in 2009. She received specialist licence in paediatrics in 2015 and was appointed as a docent of experimental paediatrics in 2018 (University of Turku). She is currently working as clinical lecturer at the department of pediatrics at University of Turku and as specialist at the Unit for Rare Diseases, Turku University Hospital. She participates in neonatal screening for severe immunodeficiencies and in laboratory diagnostics of immunodeficiencies. Training for subspecialty in pediatric infections and immunodeficiencies is ongoing.

Teaching

Docent Lempainen works as clinical lecturer in pediatrics (part-time) since January 2017. 

Research

Docent Lempainen’s thesis in 2009 focused on the pathogenesis of type 1 diabetes. Since then her research work has further focused on the heterogeneity of type 1 diabetes pathogenesis. In 2011 she worked as visiting researcher in the BabyDiab-diabetes study group in  Munich, Germany. Her current research interests comprise the etiology of beta-cell autoimmunity in respect of immunological, genetic and epigenetic factors and disturbances in early microbial contacts and are a part of the prospective Diabetes Prediction and Prevention (DIPP) study. In addition, she participates in research projects aiming at early detection of bacterial and viral infections in infants and children in order to avoid unnecessary antibiotic exposure. Since January 2020 docent Lempainen is the principal investigator of the Immunogenetics laboratory and PI and member of steering committee in the DIPP study at the University of Turku.

Publications

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Long-Lasting T Cell Responses in BNT162b2 COVID-19 mRNA Vaccinees and COVID-19 Convalescent Patients (2022)

Frontiers in Immunology
Hurme Antti, Jalkanen Pinja, Heroum Jemna, Liedes Oona., Vara Saimi, Melin Merit, Teräsjärvi Johanna, He Qiushui, Pöysti Sakari, Hänninen Arno, Oksi Jarmo, Vuorinen Tytti, Kantele Anu, Tähtinen Paula A., Ivaska Lauri, Kakkola Laura, Lempainen Johanna, Julkunen Ilkka
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Comparative analysis of COVID-19 vaccine responses and third booster dose-induced neutralizing antibodies against Delta and Omicron variants (2022)

Nature Communications
Belik M, Jalkanen P, Lundberg R, Reinholm A, Laine L, Väisänen E, Skön M, Tähtinen PA, Ivaska L, Pakkanen SH, Häkkinen HK, Ortamo E, Pasternack A, Ritvos MA, Naves RA, Miettinen S, Sironen T, Vapalahti O, Ritvos O, Österlund P, Kantele A, Lempainen J, Kakkola L, Kolehmainen P, Julkunen I
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage (2022)

Diabetologia
Sioofy-Khojine Amir-Babak, Richardson Sarah J., Locke Jonathan M., Oikarinen Sami, Nurminen Noora, Laine Antti-Pekka, Downes Kate, Lempainen Johanna, Todd John A., Veijola Riitta, Ilonen Jorma, Knip Mikael, Morgan Noel G., Hyöty Heikki, Peakman Mark, Eichmann Martin
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))