Kaisa Ivaska-Papaioannou profile picture
Kaisa
Ivaska-Papaioannou
Docent, Institute of Biomedicine
University Lecturer, Institute of Biomedicine
PhD, Associate professor (docent)
Bone and Energy Metabolism, BoneLab Turku

Contact

+358 29 450 4622
+358 50 407 6533
Kiinamyllynkatu 10
20520
Turku

Areas of expertise

bone
bone cell biology
bone metabolism
bone turnover markers
bone marrow adiposity
osteoporosis
diabetes
biomedicine
cell biology

Biography

Senior Lecturer in Cell Biology and Metabolism

Docent in Cell Biology 2012

Teaching

  • Cell biology and histology for students in Medicine (first year) and Biomedicine (Bachelor’s Degree Programme).
  • Textbooks we use: Alberts et al. Essential Cell Biology, Alberts et al. Molecular BIology of the Cell, Young et al. Wheater's Functional Histology.
  • Laboratory course "Cell and Molecular Biology (laboratory work)" for students in Biomedicine
  • Laboratory course "Methods in Cell Biology" and for medical students selected for Molecular Medicine Research Track (2-yr programme).
  • Mentoring students in biomedicine (3-yr Bachelor’s Degree Programme).
  • Participating actively in the planning of the curriculum (in particular, first year BSc studies).

Research

Bone and energy metabolism

Our reserach group is interested in the crosstalk between bone cells and energy metabolism.

Bone is not only a structural organ but interacts with other cell types in the bone marrow microenvironment and iwith extra-skeletal cells via secreted hormone-like factors. Our current research focuses on role of these bone-derived hormones, or osteokines, in local and whole body energy metabolism, and the interactions between bone-forming osteoblasts and bone marrow adipocytes in the bone microenvironment. We are also interested in the effects of type 2 diabetes on bone cells and bone metabolism. Our long term goal is to understand how changes in energy metabolism affect bone cells, bone-derived hormones, bone turnover and bone microenvironment. We use cell culture and cell-based methods, in vivo models and patient samples obtained from clinical collaborators.

Group members: Milja Arponen (doctoral researcher), Niki Jalava (doctoral researcher), Nicko Widjaja (doctoral researcher), Ronja Ojala (doctoral researcher, Turku PET Centre), Aapo Alhokankare (undergraduate student), Iida Karhu (undergraduate student)

Funding: Academy of Finland, Laboratoriolääketieteen edistämissäätiö, Turku University Foundation, Diabetes Wellness Finland

Publications

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Bone marrow metabolism is affected by body weight and response to exercise training varies according to anatomical location (2023)

Diabetes, Obesity and Metabolism
Ojala R, Hentilä J, Lietzén MS, Arponen M, Heiskanen MA, Honkala SM, Virtanen H, Koskensalo K, Lautamäki R, Löyttyniemi E, Parkkola R, Heinonen OJ, Malm T, Lahti L, Rinne J, Eskola O, Rajander J, Pietiläinen KH, Kaprio J, Ivaska KK, Hannukainen JC
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Guidelines for Biobanking of Bone Marrow Adipose Tissue and Related Cell Types: Report of the Biobanking Working Group of the International Bone Marrow Adiposity Society (2021)

Frontiers in Endocrinology
Lucas S, Tencerova M, von der Weid B, Andersen TL, Attané C, Behler-Janbeck F, Cawthorn WP, Ivaska KK, Naveiras O, Podgorski I, Reagan MR, van der Eerden BCJ; on behalf of the Biobanking Working Group for the International Bone Marrow Adiposity Society (BMAS)
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))