Nafis Rahman profile picture
Nafis
Rahman
Docent, Faculty of Medicine
Clinical Lecturer, Institute of Biomedicine
MD, PhD

Contact

+358 29 450 4637
+358 50 477 3022
Kiinamyllynkatu 10
20520
Turku

Areas of expertise

endocrine-related cancer
gonadotropins
hypothalamus-pituitary-gonadal axis
ardenocortical tumours
novel treatment strategies

Biography

Docent of Physiology, University of Turku, Turku, Finland (2005)  & Docent of Medicine, Medical University of Bialystok, Poland (2016); Doctor of Medical Sciences (Ph.D.), Medical University of Lodz, Poland  (1995); Specialization in Obstetrics & Gynecology, Medical University of Lodz, Poland  (1995); Licentiate in Medicine, Medical University of Lodz, Poland  (1991)

Working at the University of Turku: from 1996 - 

Postdoctoral training: Prof Ilpo Huhtaniemi group 1996 - 1998

Visiting professorships  Current: Medical University of Bialystok, Bialystok, Poland; Former: FIU College of Medicine, Miami, FL, USA

Editor in chief from 2016 https://www.journals.elsevier.com/reproductive-biology/

Teaching

Teach at the University of Turku, Faculty of Medicine, medical curriculum students: Physiology, Endocrinology, reproductive Endocrinology; Reproductive Biology courses

Received the teacher of the year award (Vuoden Opettaja) in 2005 from the Student Union & Rector of the University of Turku.

Research

Our study the underlying molecular mechanisms of hormonally regulated cancers (i.e. prostate, ovarian, testicular and adrenocortical), search for their novel biomarkers and treatment. We recently tested the potential of tumor specific zona pellucida antigen-3 immunization to enhance therapeutic effects in several hormonally regulated cancers. We have used successfully conjugated lytic peptides to eradicate only cancer cells through their specific gonadotropin receptors (such as lhcgr). We use transgenic murine endocrine cancer metastatic disease models and immortalized cell lines to test the feasibility of novel treatment strategies starting at cellular, in vivo in TG mice and finally aim for human clinical trials. 

Publications

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Features of the fetal gonad in androgen synthesis in the postpubertal testis are preserved in complete androgen insensitivity syndrome due to a novel genetic splice site donor variant in androgen receptor gene intron 1 (2019)

Journal of Steroid Biochemistry and Molecular Biology
Katarzyna Jarzabek, Mariusz Koda, Marcin Chrusciel, Luiza Kanczuga-Koda, Agnieszka Sobczynska-Tomaszewska, Nafis A. Rahman, Slawomir Wolczynski
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

GnRH antagonist treatment of malignant adrenocortical tumors (2019)

Endocrine-Related Cancer
Doroszko M, Chrusciel M, Stelmaszewska J, Slezak T, Anisimowicz S, Plöckinger U, Quinkler M, Bonomi M, Wolczynski S, Huhtaniemi I, Toppari J, Rahman NA
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Functional Implications of LH/hCG Receptors in Pregnancy-Induced Cushing Syndrome (2017)

Journal of the Endocrine Society
Ursula Plöckinger, Marcin Chrusciel, Milena Doroszko, Wolfgang Saeger, Oliver Blankenstein, Katharina Weizsäcker, Matthias Kroiss, Kathrin Hauptmann, Cornelia Radke, Alexander Pöllinger, Nikolaus Tiling, Thomas Steinmüller, Ilpo Huhtaniemi, Marcus Quinkler, Jerome Bertherat, André Lacroix, Nafis Rahman
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))