Tove Grönroos profile picture
Senior Research Fellow, Turku PET Centre
Docent, Department of Clinical Medicine
Head of Preclinical PET Imaging


+358 29 450 3839
+358 50 356 2822
Tykistökatu 6

Areas of expertise

energy metabolism
experimental radiotherapy


Our translational research focuses on evaluating and validating PET tracers for imaging the tumor microenvironment. We are especially interested in approaches for determining the level of radioresistance in solid tumors that affect radiotherapy treatment outcomes in cancer patients. Such tracers can be utilized for treatment planning and follow-up purposes in clinical settings. Another objective is to re-evaluate some existing tracers for their possible use as cancer imaging tools or to measure changes in cancer-dependent metabolism pathways on a whole-body level, which might affect treatment outcomes. We combine PET technology with state-of-the-art technologies for molecular biology utilizing cell lines, tumor models, and patient-derived samples.


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Small animal PET with spontaneous inhalation of 15O-labelled oxygen gases: Longitudinal assessment of cerebral oxygen metabolism in a rat model of neonatal hypoxic-ischaemic encephalopathy (2023)

Journal of Cerebral Blood Flow and Metabolism
Shimochi Saeka, Ihalainen Jukka, Parikka Vilhelmiina, Kudomi Nobuyuki, Tolvanen Tuula, Hietanen Ari, Kokkomäki Esa, Johansson Stefan, Tsuji Masahiro, Kanaya Shigehiko, Yatkin Emrah, Grönroos Tove J., Iida Hidehiro
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

[F-18]Fluoride uptake in various bone types and soft tissues in rat (2023)

EJNMMI Research
Savisto Nina, Grönroos Tove J, Oikonen Vesa, Rajander Johan, Löyttyniemi Eliisa, Bergman Jörgen, Forsback Sari, Solin Olof, Haaparanta-Solin Merja
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246-Sensitive Disease Subtype (2022)

Molecular Cancer Therapeutics
Cvrljevic Anna N. Butt Umar, Huhtinen Kaisa, Grönroos Tove J., Böckelman Camilla, Lassus Heini, Butzow Ralf, Haglund Caj, Kaipio Katja, Arsiola Tiina, Laajala Teemu D., Connolly Denise C, Ristimäki Ari, Carpen Olli, Pouwels Jeroen, Westermarck Jukka
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

CIP2A interacts with TopBP1 and drives basal-like breast cancer tumorigenesis (2021)

Cancer Research
Laine Anni, Nagelli Srikar G., Farrington Caroline, Butt Umar, Cvrljevic Anna N., Vainonen Julia P., Feringa Femke M., Grönroos Tove J., Gautam Prson, Khan Sofia, Sihto Harri, Qiao Xi, Pavic Karolina, Connolly Denise C., Kronqvist Pauliina, Elo Laura L., Maurer Jochen, Wennerberg Krister, Medema Rene H., Joensuu Heikki, Peuhu Emilia, de Visser Karin, Narla Goutham, Westermarck Jukka
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))