Urpo
Lamminmäki
Professor, Biotechnology
InFLAMES Flagship
PhD
Areas of expertise
Antibody engineering
Bioaffinity assays
in vitro diagnostics
Teaching
Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry
Diagnostics
Research
My research is largely focused to recombinant antibodies and other bioaffinity molecules. I am interested in developing techniques used for tailoring such molecules as well as applications of these molecules in various fields including diagnostics, drug development and biomarker discovery.
Publications
Development of anti-immunocomplex specific antibodies and non-competitive time-resolved fluorescence immunoassay for the detection of estradiol (2019)
Analytical and Bioanalytical Chemistry
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer-Associated CA125 from Benign Sources (2019)
The Journal of Applied Laboratory Medicine
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma (2019)
PLoS ONE
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
A homogeneous assay for rapid detection of cyanobacterial peptide hepatotoxins: Microcystins and nodularins (2019)
EuroMedLab 2019, Clinica Chimica Acta
(Muu (O2))
A Nanoparticle-Based Approach for the Detection of Extracellular Vesicles (2019)
Scientific Reports
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Detection of Food Taints and Contaminants Using Novel Engineered Antibodies (2019)
(Vertaisarvioitu artikkeli kokoomateoksessa (A3))A cancer-specific detection of serum CA125 improves differential diagnosis of epithelial ovarian cancer from benign conditions. (2018)
Clinical Cancer Research
(Muu (O2))
Array-in-well epitope mapping of phage-displayed antibodies (2018)
(Vertaisarvioitu artikkeli kokoomateoksessa (A3))Molecular tools for selective recovery and detection of lignin-derived molecules (2018)
Green Chemistry
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
CA125 glycoform assay improves the performance of conventional CA125 in the diagnostics of epithelial ovarian cancer (2018)
International Journal of Gynecological Cancer
(Muu (O2))