Xiang-Guo Li profile picture
Xiang-Guo
Li
Assistant Professor, Turku PET Centre
Assistant Professor
Radiochemistry, Radiopharmaceuticals, InFLAMES Flagship

Contact

Kiinamyllynkatu 10
20520
Turku

Areas of expertise

Radiochemistry
Radiopharmaceuticals
PET imaging
New drug development

Biography

I am a radiochemist and medicinal chemist working at Turku PET Centre, University of Turku, Finland. I received my PhD degree from the Institute of Biomedicine, Faculty of Medicine, University of Turku, in 2008. Then I was at a Post-doctoral position funded by the Academy of Finland during 2010-2012. I received my Docentship in 2012 from University of Turku. Since 2013, I have been working at Turku PET Centre. At present, I work as an Assistant Professor in Radiochemistry, and Principal Investigator in the InFLAMES Research Flagship.

Teaching

I teach in the courses of Radiopharmaceutical Chemistry, Radiolabeling techniques, Measuring techniques in radiochemistry, PET Basics, and supervise BSc, MSc and PhD students.

Research

Basic research in radiochemistry including methodological development for radiosynthesis and radiolabeling techniques. We have been able to radiolabel many types of molecules including small organic compounds, peptides, antibody and antibody fragments, oligonucleotides, oligosaccharides etc.

Development of new radiopharmaceuticals for PET imaging of inflammatory diseases and immunological diseases.

The radiolabeled molecules are for imaging diseases or for studying disease machanisms with PET.



Publications

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Highlight selection of radiochemistry and radiopharmacy developments by editorial board (2024)

EJNMMI Radiopharmacy and Chemistry
Toyohara Jun, Vugts Danielle, Kiss Oliver C., Todde Sergio, Li Xiang-Guo, Liu Zhibo, Yang Zhi, Gillings Nic, Cazzola Emiliano, Szymanski Wiktor, Meulen Nick van der, Reilly Raymond, Taddei Carlotta, Schirrmacher Ralf, Li Zijing, Lagebo Yohannes Jorge, Bentaleb Naoual, Souza Albernaz Marta de, Lapi Suzanne, Ramogida Caterina, Mukherjee Archana, Ajenjo Javier, Deuther-Conrad Winnie, Bourdeau Cécile
(Kirjoitus tai data-artikkeli tieteellisessä aikakauslehdessä (B1))

Vascular adhesion protein-1-targeted PET imaging in autoimmune myocarditis (2023)

Journal of Nuclear Cardiology
Jahandideh Arghavan, Virta Jenni, Li Xiang-Guo, Liljenbäck Heidi, Moisio Olli, Ponkamo Jesse, Rajala Noora, Alix Marion, Lehtonen Jukka, Mäyränpää Mikko I., Salminen Tiina A., Knuuti Juhani, Jalkanen Sirpa, Saraste Antti, Roivainen Anne
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

High folate receptor expression in gliomas can be detected in vivo using folate-based positron emission tomography with high tumor-to-brain uptake ratio divulging potential future targeting possibilities (2023)

Frontiers in Immunology
Miner Maxwell W. G., Liljenbäck Heidi, Virta Jenni, Kärnä Salli, Viitanen Riikka, Elo Petri, Gardberg Maria, Teuho Jarmo, Saipa Piritta, Rajander Johan, Mansour A Mansour Hasan, Cleveland Nathan A., Low Philip S., Li Xiang-Guo, Roivainen Anne
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Detection of Intestinal Inflammation by Vascular Adhesion Protein-1-Targeted [68Ga]Ga-DOTA-Siglec-9 Positron Emission Tomography in Murine Models of Inflammatory Bowel Disease (2023)

Molecular Imaging and Biology
Bhowmik Achol A., Heikkilä Taina R. H., Polari Lauri, Virta Jenni, Liljenbäck Heidi, Moisio Olli, Li Xiang-Guo, Viitanen Riikka, Jalkanen Sirpa, Koffert Jukka, Toivola Diana M., Roivainen Anne
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))