Research at the Department of Otorhinolaryngology – Head and Neck Surgery

The research activities of the Department of Otorhinolaryngology – Head and Neck Surgery cover a wide range of areas that are related to the field. 

  • Audiology
  • Biomaterial research
  • Cell biology and cancer research
  • Deep neck infections
  • Experimental and microvascular surgery
  • ORL endoscopy
  • Otoneurology
  • Rhinology: rhinomanometry, acoustic rhinometry, sinusitis
  • Tonsil surgery

The Department has published doctoral theses since 1952. The Department has generated a large number of permanent cell lines from head and neck malignancies. In addition to radio and chemosensitivity and prognostic factors, these cell lines and the clinical information gained from them have formed the basis for fruitful collaboration with a number of scientists in Finland and abroad.

The Department’s biomaterial research and the clinical applications of bioactive glass have led to several clinical applications. This research area is carried out largely in collaboration with the Institute of Dentistry.

Recent publications

A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels (2014)

Journal of Cancer Research and Clinical Oncology
Manuel Tonigold, Annette Rossmann, Marie Meinold, Michael Bette, Melanie Märken, Katharina Henkenius, Anne C. Bretz, Gavin Giel, Chengzhong Cai, Fiona R. Rodepeter, Vladimir Beneš, Reidar Grénman, Thomas E. Carey, Hermann Lage, Thorsten Stiewe, Andreas Neubauer, Jochen A. Werner, Cornelia Brendel, Robert Mandic
(Refereed journal article or data article (A1))

Recent doctoral dissertations

A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels (2014)

Journal of Cancer Research and Clinical Oncology
Manuel Tonigold, Annette Rossmann, Marie Meinold, Michael Bette, Melanie Märken, Katharina Henkenius, Anne C. Bretz, Gavin Giel, Chengzhong Cai, Fiona R. Rodepeter, Vladimir Beneš, Reidar Grénman, Thomas E. Carey, Hermann Lage, Thorsten Stiewe, Andreas Neubauer, Jochen A. Werner, Cornelia Brendel, Robert Mandic
(Refereed journal article or data article (A1))