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Med kuvitus 589

Research at the Institute of Biomedicine

Research at the Institute of Biomedicine is divided into three functional units: 1) Infection and Immunity, 2) Integrative Physiology and Pharmacology and 3) Cancer research. Research at our Institute includes both biomedical basic research and translational research, and the unit division expresses our research priorities.

We encourage creative interdisciplinary combination of research topics via collaboration of the individual research groups and the three units. In addition, we collaborate locally with clinical researchers, with other institutes of our university and with the Åbo Akademi University. We are also widely networked with numerous national and international universities and public and private research institutes.

Research Units

Infection and Immunity (director Cecilia Söderberg-Nauclér)

Integrative Physiology and Pharmacology (director Noora Kotaja)

Cancer Research (director Maria Sundvall)

Research services

Core Facilities of the Institute of Biomedicine

Recent publications

Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure (2018)

International Journal of Molecular Sciences

Konings GF, Saarinen N, Delvoux B, Kooreman L, Koskimies P, Krakstad C, Fasmer KE, Haldorsen IS, Zaffagnini A, Häkkinen MR, Auriola S, Dubois L, Lieuwes N, Verhaegen F, Schyns LE, Kruitwagen RF; ENITEC Consortium, Xanthoulea S, Romano A.

(Refereed journal article or data article (A1))

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression (2018)

Nature Communications

Vazquez MJ, Toro CA, Castellano JM, Ruiz-Pino F, Roa J, Beiroa D, Heras V, Velasco I, Dieguez C, Pinilla L, Gaytan F, Nogueiras R, Bosch MA, Ronnekleiv OK, Lomniczi A, Ojeda SR, Tena-Sempere M

(Refereed journal article or data article (A1))

Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism (2018)

JCI Insight

Hakan Cangul, Xiao-Hui Liao, Erik Schoenmakers, Jukka Kero, Sharon Barone, Panudda Srichomkwun, Hideyuki Iwayama, Eva G. Serra, Halil Saglam, Erdal Eren, Omer Tarim, Adeline K. Nicholas, Ilona Zvetkova, Carl A. Anderson, Fiona E. Karet Frankl, Kristien Boelaert, Marja Ojaniemi, Jarmo Jääskeläinen, Konrad Patyra, Christoffer Löf, E. Dillwyn Williams, UK10K Consortium, Manoocher Soleimani, Timothy Barrett, Eamonn R. Maher, V. Krishna Chatterjee, Samuel Refetoff, Nadia Schoenmakers

(Refereed journal article or data article (A1))

Functional Characterization of MicroRNA-27a-3p Expression in Human Polycystic Ovary Syndrome (2018)

Endocrinology

Mingming Wang, Jing Sun, Bo Xu, Marcin Chrusciel, Jun Gao, Maciei Bazert, Joanna Stelmaszewska, Yunyun Xu, Hongwen Zhang, Leszek Pawelczyk, Fei Sun, Suk Ying Tsang, Nafis Rahman, Sławomir Wołczyński, Xiangdong Li

(Refereed journal article or data article (A1))

Clinically variable nemaline myopathy in a three-generation family caused by mutation of the skeletal muscle alpha-actin gene (2018)

Neuromuscular Disorders

Vilma-Lotta Lehtokari, Maria Gardberg, Katarina Pelin, Carina Wallgren-Pettersson

(Refereed journal article or data article (A1))

Recent doctoral dissertations

Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure (2018)

International Journal of Molecular Sciences

Konings GF, Saarinen N, Delvoux B, Kooreman L, Koskimies P, Krakstad C, Fasmer KE, Haldorsen IS, Zaffagnini A, Häkkinen MR, Auriola S, Dubois L, Lieuwes N, Verhaegen F, Schyns LE, Kruitwagen RF; ENITEC Consortium, Xanthoulea S, Romano A.

(Refereed journal article or data article (A1))

SIRT1 mediates obesity- and nutrient-dependent perturbation of pubertal timing by epigenetically controlling Kiss1 expression (2018)

Nature Communications

Vazquez MJ, Toro CA, Castellano JM, Ruiz-Pino F, Roa J, Beiroa D, Heras V, Velasco I, Dieguez C, Pinilla L, Gaytan F, Nogueiras R, Bosch MA, Ronnekleiv OK, Lomniczi A, Ojeda SR, Tena-Sempere M

(Refereed journal article or data article (A1))

Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism (2018)

JCI Insight

Hakan Cangul, Xiao-Hui Liao, Erik Schoenmakers, Jukka Kero, Sharon Barone, Panudda Srichomkwun, Hideyuki Iwayama, Eva G. Serra, Halil Saglam, Erdal Eren, Omer Tarim, Adeline K. Nicholas, Ilona Zvetkova, Carl A. Anderson, Fiona E. Karet Frankl, Kristien Boelaert, Marja Ojaniemi, Jarmo Jääskeläinen, Konrad Patyra, Christoffer Löf, E. Dillwyn Williams, UK10K Consortium, Manoocher Soleimani, Timothy Barrett, Eamonn R. Maher, V. Krishna Chatterjee, Samuel Refetoff, Nadia Schoenmakers

(Refereed journal article or data article (A1))

Functional Characterization of MicroRNA-27a-3p Expression in Human Polycystic Ovary Syndrome (2018)

Endocrinology

Mingming Wang, Jing Sun, Bo Xu, Marcin Chrusciel, Jun Gao, Maciei Bazert, Joanna Stelmaszewska, Yunyun Xu, Hongwen Zhang, Leszek Pawelczyk, Fei Sun, Suk Ying Tsang, Nafis Rahman, Sławomir Wołczyński, Xiangdong Li

(Refereed journal article or data article (A1))

Clinically variable nemaline myopathy in a three-generation family caused by mutation of the skeletal muscle alpha-actin gene (2018)

Neuromuscular Disorders

Vilma-Lotta Lehtokari, Maria Gardberg, Katarina Pelin, Carina Wallgren-Pettersson

(Refereed journal article or data article (A1))

Keywords

Institute of Biomedicine