Research at the Research Centre of Applied and Preventive Cardiovascular Medicine

Research projects

The Cardiovascular Risk in Young Finns Study (YFS) - Epidemiologic study on atherosclerotic precursors in Finnish children and young adults

The Cardiovascular Risk in Young Finns Study is one of the largest follow-up studies into cardiovascular risk from childhood to adulthood. The main aim is to determine the contribution made by childhood lifestyle, biological, and psychological measures to the risk of cardiovascular diseases in adulthood.

Project Leader: Academy Professor Olli Raitakari

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The STRIP Project - A Prospective Randomized Trial of Atherosclerosis Prevention in Infancy and Childhood - An Epidemiological Study

The STRIP study is unique worldwide; no other study has started dietary intervention in infancy and continued it for 20 years, and simultaneously collected data with repeated measurements on a vast number of risk factors and subclinical markers for cardiovascular health.

The main purpose of the STRIP Study (Special Turku Coronary Risk Factor Intervention Project) is the prevention of atherosclerosis and coronary heart disease by a dietary intervention which began in infancy and has continued to early adulthood. The trial was launched in 1990 when 1062 7-month-old children and their families were enrolled. Half of the families have received individualized dietary and other life-style counseling at least twice a year whereas the rest of the families have served as a control group. The STRIP Study intervention continued until the participants reached the age of 20 years.

Project Leader: Academy Professor Olli Raitakari

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Recent publications of the Research Centre of Applied and Preventive Cardiovascular Medicine

A Genome-Wide Approach to Children's Aggressive Behavior: The EAGLE consortium (2016)

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Irene Pappa, Beate St Pourcain, Kelly Benke, Alana Cavadino, Christian Hakulinen,
Michel G. Nivard, Ilja M. Nolte, Carla M. T. Tiesler, Marian J. Bakermans-Kranenburg,
Gareth E. Davies, David M. Evans, Marie-Claude Geoffroy, Harald Grallert,
Maria M. Groen-Blokhuis, James J. Hudziak, John P. Kemp,
Liisa Keltikangas-Järvinen, George McMahon, Viara R. Mileva-Seitz, Ehsan Motazedi,
Christine Power, Olli T. Raitakari, Susan M. Ring, Fernando Rivadeneira,
Alina Rodriguez, Paul A. Scheet, Ilkka Seppälä, Harold Snieder, Marie Standl,
Elisabeth Thiering, Nicholas J. Timpson, Rene Veenstra, Fleur P. Velders,
Andrew J. O. Whitehouse, George Davey Smith, Joachim Heinrich, Elina Hypponen,
Terho Lehtimäki, Christel M. Middeldorp, Albertine J. Oldehinkel, Craig E. Pennell, Dorret I. Boomsma, Henning Tiemeier
(Refereed journal article or data article (A1))

Associations with intraocular pressure across Europe: The European Eye Epidemiology (E3) Consortium. (2016)

European Journal of Epidemiology
Anthony P. Khawaja, Henriët Springelkamp, Catherine Creuzot-Garcher, Cécile Delcour, tAlbert Hofman, René Höhn, Adriana I. Iglesias, Roger C. W. Wolfs, Jean-François Korobelnik, Rufino Silva, Fotis Topouzis, Katie M. Williams, Alain M. Bron, Gabriëlle H. S. Buitendijk, Maria da Luz Cachulo, Audrey Cougnard-Grégoire, Jean-François Dartigues, Christopher J. Hammond, Norbert Pfeiffer, Angeliki Salonikiou, Cornelia M. van Duijn, Johannes R. Vingerling, Robert N. Luben, Alireza Mirshahi, Julia Lamparter, Caroline C. W. Klaver, Nomdo M. Jansonius, Paul J. Foster; On behalf of the European Eye Epidemiology (E³) Consortium
(Refereed journal article or data article (A1))