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Research at the Research Centre of Applied and Preventive Cardiovascular Medicine

Research projects

The Cardiovascular Risk in Young Finns Study (YFS) - Epidemiologic study on atherosclerotic precursors in Finnish children and young adults

The Cardiovascular Risk in Young Finns Study is one of the largest follow-up studies into cardiovascular risk from childhood to adulthood. The main aim is to determine the contribution made by childhood lifestyle, biological, and psychological measures to the risk of cardiovascular diseases in adulthood.

Project Leader: Academy Professor Olli Raitakari

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The STRIP Project - A Prospective Randomized Trial of Atherosclerosis Prevention in Infancy and Childhood - An Epidemiological Study

The STRIP study is unique worldwide; no other study has started dietary intervention in infancy and continued it for 20 years, and simultaneously collected data with repeated measurements on a vast number of risk factors and subclinical markers for cardiovascular health.

The main purpose of the STRIP Study (Special Turku Coronary Risk Factor Intervention Project) is the prevention of atherosclerosis and coronary heart disease by a dietary intervention which began in infancy and has continued to early adulthood. The trial was launched in 1990 when 1062 7-month-old children and their families were enrolled. Half of the families have received individualized dietary and other life-style counseling at least twice a year whereas the rest of the families have served as a control group. The STRIP Study intervention continued until the participants reached the age of 20 years.

Project Leader: Academy Professor Olli Raitakari

Read more about the project

Recent publications of the Research Centre of Applied and Preventive Cardiovascular Medicine

Childhood 25-OH Vitamin D Levels and Carotid Intima-Media Thickness in Adulthood: The Cardiovascular Risk in Young Finns Study (2015)

Journal of Clinical Endocrinology and Metabolism

Juonala M, Voipio A, Pahkala K, Viikari JSA, Mikkila V, Kahonen M, Hutri-Kahonen N, Jula A, Burgner D, Sabin MA, Marniemi J, Loo BM, Laitinen T, Jokinen E, Taittonen L, Magnussen CG, Raitakari OT

(Refereed journal article or data article (A1))

Coronary heart disease risk factors, coronary artery calcification and epicardial fat volume in the Young Finns Study (2015)

EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging

Hartiala O, Magnussen CG, Bucci M, Kajander S, Knuuti J, Ukkonen H, Saraste A, Rinta-Kiikka I, Kainulainen S, Kähönen M, Hutri-Kähönen N, Laitinen T, Lehtimäki T, Viikari JS, Hartiala J, Juonala M, Raitakari OT

(Refereed journal article or data article (A1))

Psychological wellbeing in 20-year-old adults receiving repeated lifestyle counselling since infancy (2015)

Acta Paediatrica

Kaseva K, Pulkki-Raback L, Elovainio M, Pahkala K, Keltikangas-Jarvinen L, Hintsanen M, Hakulinen C, Lagstrom H, Jula A, Niinikoski H, Ronnemaa T, Viikari J, Simell O, Raitakari O

(Refereed journal article or data article (A1))

Factors Affecting Tracking of Blood Pressure from Childhood to Adulthood: The Childhood Determinants of Adult Health Study (2015)

Journal of Pediatrics

Kelly RK, Thomson R, Smith KJ, Dwyer T, Venn A, Magnussen CG

(Refereed journal article or data article (A1))

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption (2015)

Molecular Psychiatry

Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, Teumer A, Yu K, Marques-Vidal P, Rawal R, Manichaikul A, Wojczynski MK, Vink JM, Zhao JH, Burlutsky G, Lahti J, Mikkila V, Lemaitre RN, Eriksson J, Musani SK, Tanaka T, Geller F, Luan J, Hui J, Magi R, Dimitriou M, Garcia ME, Ho WK, Wright MJ, Rose LM, Magnusson PKE, Pedersen NL, Couper D, Oostra BA, Hofman A, Ikram MA, Tiemeier HW, Uitterlinden AG, van Rooij FJA, Barroso I, Johansson I, Xue L, Kaakinen M, Milani L, Power C, Snieder H, Stolk RP, Baumeister SE, Biffar R, Gu F, Bastardot F, Kutalik Z, Jacobs DR, Forouhi NG, Mihailov E, Lind L, Lindgren C, Michaelsson K, Morris A, Jensen M, Khaw KT, Luben RN, Wang JJ, Mannisto S, Perala MM, Kahonen M, Lehtimaki T, Viikari J, Mozaffarian D, Mukamal K, Psaty BM, Doring A, Heath AC, Montgomery GW, Dahmen N, Carithers T, Tucker KL, Ferrucci L, Boyd HA, Melbye M, Treur JL, Mellstrom D, Hottenga JJ, Prokopenko I, Tonjes A, Deloukas P, Kanoni S, Lorentzon M, Houston DK, Liu Y, Danesh J, Rasheed A, Mason MA, Zonderman AB, Franke L, Kristal BS, Karjalainen J, Reed DR, Westra HJ, Evans MK, Saleheen D, Harris TB, Dedoussis G, Curhan G, Stumvoll M, Beilby J, Pasquale LR, Feenstra B, Bandinelli S, Ordovas JM, Chan AT, Peters U, Ohlsson C, Gieger C, Martin NG, Waldenberger M, Siscovick DS, Raitakari O, Eriksson JG, Mitchell P, Hunter DJ, Kraft P, Rimm EB, Boomsma DI, Borecki IB, Loos RJF, Wareham NJ, Vollenweider P, Caporaso N, Grabe HJ, Neuhouser ML, Wolffenbuttel BHR, Hu FB, Hypponen E, Jarvelin MR, Cupples LA, Franks PW, Ridker PM, van Duijn CM, Heiss G, Metspalu A, North KE, Ingelsson E, Nettleton JA, van Dam RM, Chasman DI

(Refereed journal article or data article (A1))

Keywords

Cardiovascular Medicine (CAPC)