Frontiers of Science Seminar: MD Tuomas Tammela
Time
14.12.2023 at 12.00 - 13.00
Frontiers of Science
December 14th at 12:00
On-site event
Presidentti auditorium
MD Tuomas Tammela, Sloan Kettering Institute; Memorial Sloan Kettering Cancer Center, US
Functional interrogation of intra-tumoral heterogeneity
Host: Klaus Elenius (klaele@utu.fi)
Coffee and sandwich at 11:45, first come first served!
Six students and early-career postdocs are welcome to have a lunch in restaurant Mauno and discuss with Tuomas Tammela after the seminar. This is a great possibility to learn hosting skills in friendly environment and create connections for future. Every student is welcome to join, in spite of which research group they belong to. BioCity Turku will offer the lunch.
If you got interested, please send an email to biocityturku@bioscience.fi
The Tammela lab is interested in understanding the remarkable phenotypic heterogeneity of cancer cells within tumors. We approach this question using a combination of sophisticated genetically engineered mouse models, single-cell approaches, tracing and ablation of distinct tumor cell lineages, CRISPR-mediated gene regulation, and advanced imaging techniques. We utilize the exceptional resources developed by our MSK collaborators, such as organoids and xenografts, for the translation of our findings into new treatments for human cancer. Our goal is to discover pathways that drive distinct cellular phenotypes and to develop new therapeutic concepts aimed at reducing cellular heterogeneity in tumors.
ed publications
M Kim, M Panagiotakopoulou, C Chen, SB Ruiz, K Ganesh, T Tammela, ..., 2023. Micro-engineering and nano-engineering approaches to investigate tumour ecosystems. Nature Reviews Cancer, 1-19
SR Torborg, Z Li, JE Chan, T Tammela. 2022. Cellular and molecular mechanisms of plasticity in cancer. Trends in Cancer 8 (9), 735-746
Marjanovic ND, Hofree M, Chan JE, … , Rekhtman N, Massion PP, Poirier JT, Mazutis L, Li R, Lee JH, Amon A, Rudin CM, Jacks T, Regev A, Tammela T. (2020). Emergence of a High-Plasticity Cell State during Lung Cancer Evolution. Cancer Cell, 38(2):229-246
General information
• You can download and save all the autumn 2023 FoS-seminars to your calendar from here: https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/
• Registration is not needed, participation list is circulated in the audience
• If you are a student and later wish to get a certificate of attendance from the Frontier of Science seminars, print out the seminar diary and after the seminar ask the BioCity coordinator to sign it https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/
• Please note that any audio or video recording of the seminars is strictly forbidden.
December 14th at 12:00
On-site event
Presidentti auditorium
MD Tuomas Tammela, Sloan Kettering Institute; Memorial Sloan Kettering Cancer Center, US
Functional interrogation of intra-tumoral heterogeneity
Host: Klaus Elenius (klaele@utu.fi)
Coffee and sandwich at 11:45, first come first served!
Six students and early-career postdocs are welcome to have a lunch in restaurant Mauno and discuss with Tuomas Tammela after the seminar. This is a great possibility to learn hosting skills in friendly environment and create connections for future. Every student is welcome to join, in spite of which research group they belong to. BioCity Turku will offer the lunch.
If you got interested, please send an email to biocityturku@bioscience.fi
The Tammela lab is interested in understanding the remarkable phenotypic heterogeneity of cancer cells within tumors. We approach this question using a combination of sophisticated genetically engineered mouse models, single-cell approaches, tracing and ablation of distinct tumor cell lineages, CRISPR-mediated gene regulation, and advanced imaging techniques. We utilize the exceptional resources developed by our MSK collaborators, such as organoids and xenografts, for the translation of our findings into new treatments for human cancer. Our goal is to discover pathways that drive distinct cellular phenotypes and to develop new therapeutic concepts aimed at reducing cellular heterogeneity in tumors.
ed publications
M Kim, M Panagiotakopoulou, C Chen, SB Ruiz, K Ganesh, T Tammela, ..., 2023. Micro-engineering and nano-engineering approaches to investigate tumour ecosystems. Nature Reviews Cancer, 1-19
SR Torborg, Z Li, JE Chan, T Tammela. 2022. Cellular and molecular mechanisms of plasticity in cancer. Trends in Cancer 8 (9), 735-746
Marjanovic ND, Hofree M, Chan JE, … , Rekhtman N, Massion PP, Poirier JT, Mazutis L, Li R, Lee JH, Amon A, Rudin CM, Jacks T, Regev A, Tammela T. (2020). Emergence of a High-Plasticity Cell State during Lung Cancer Evolution. Cancer Cell, 38(2):229-246
General information
• You can download and save all the autumn 2023 FoS-seminars to your calendar from here: https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/
• Registration is not needed, participation list is circulated in the audience
• If you are a student and later wish to get a certificate of attendance from the Frontier of Science seminars, print out the seminar diary and after the seminar ask the BioCity coordinator to sign it https://seafile.utu.fi/d/44a70f80ac1e46a9ad0a/
• Please note that any audio or video recording of the seminars is strictly forbidden.