Arno Hänninen profile picture
Arno
Hänninen
Adjunct Professor, Faculty of Medicine
Clinical Lecturer, Institute of Biomedicine
MD, PhD, Adj. prof.

Contact

+358 29 450 4545
+358 50 511 9870
Kiinamyllynkatu 10
20520
Turku

Areas of expertise

clinical and experimental immunology
pathogenesis of type 1 diabetes
gut microbiota

Biography

Present affiliation: Clinical teacher and Principal investigator (adj. professor), Institute of Biomedicine, University of Turku. Senior physician, Turku University Hospital Laboratory Division

Past affiliations: Academy of Finland Research Fellow; Prinicpal investigator in Center of Excellence in Cell Traffic (Academy of Finland affiliated), Postdoctoral researcher, WEHI (Walter and Eliza Hall Institute); Melbourne, Australia, PhD student and postdoc in Medical microbiology and Immunology (MediCity).

Teaching

Clinical and basic immunology, clinical microbiology.
As a clinical teacher, I have responsibilities in organizing, implementing and developing the education of medical doctors, dentists and master students in biomedicine in the fields of microbiology and immunology.
Board member in Medial Faculty's education committee

Research

My research is focused on gut microbiota and gut immune system. In particular, our interest is to understand how perturbations in gut microbiota link to autoimmunity and to the development of  type 1 (T1D) diabetes. I have a long tradition in studying aspects of lymphocyte trafficking, gut-related homing mechanisms, peripheral immune tolerance and T-cell activation mechanisms. In addition, my more recent interest is to promote and contribute to clinical studies related to my diagnostic work.
We currently investigate the role of locally induced chemokines in the initiation of lymphocyte accumulation into islets in NOD mice. As a parallel facet, we explore how gut dysbiosis disrupts peripheral tolerance mechanisms in pancreatic lymph node to find ways to interfere with this.
In a prospective study in infants (www.samitutkimus.fi), we use novel tools to study individual differences in enzymatic activities of gut microbes and their relation to the maturation of healthy microbiota.

Publications

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